Protein Alignment Spn42Da and SERPINA5

DIOPT Version :10

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 109/384 - (28%)
• Similarity: 192/384 - (50%)
• Gaps: 22/384 - (5%)

  Fly    32 TMADAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLG 96
            |:|.::.::       |:.::|..|:...|.::|.|||.||....||..|||.:.|..|:.:|||
Human    39 TVAPSSRRD-------FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLG 96

  Fly    97 --LASSDPEQIAHSFHQVLAAY---QDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVD 156
              |..|..:::...|.|:|...   :|...|.:.|.:|......|:..|...:...:|:.....:
Human    97 LNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTN 161

  Fly   157 FSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFH 221
            |..:..|...||::|.::|...|.||:..  |:|.:.:::||.|.||..|:..|....|:...|:
Human   162 FRDSAGAMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224

  Fly   222 LDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTL 286
            :..|..|:|||||.::::.|.....|....:.:||: .:.:.|.:|| ::..:..:|..|...||
Human   225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQ-GNATALFILP-SEGKMQQVENGLSEKTL 287

  Fly   287 SQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKA 351
            .:..:...:.::.|.||:|..|...:|.:|...||:|.:|:..|:... :.:...::||.::|||
Human   288 RKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSG-ISNHSNIQVSEMVHKA 351

  Fly   352 FIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQKDLPLFWGSVVR 410
            .:||:|.||.||||||.....:.|.::.:..:   .:.||...:|...  .||.|.|.|
Human   352 VVEVDESGTRAAAATGTIFTFRSARLNSQRLV---FNRPFLMFIVDNN--ILFLGKVNR 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	104/366 (28%)
SERPINA5	NP_000615.3	serpinA5_PCI	44..406	CDD:381021	107/379 (28%)