DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and serpinf1

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001004539.1	Gene:	serpinf1 / 447800	ZFINID:	ZDB-GENE-040912-2	Length:	406	Species:	Danio rerio

Alignment Length:	416	Identity:	102/416 - (24%)
Similarity:	188/416 - (45%)	Gaps:	42/416 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLGL-ALFPFPPVHTADVTMADAAHQ----------EFARRLALFSINVYGKLSGQKPGENIVFS 68
            |:|| :|........||.|.|:...:          :.|...:.|..|::.:|:.:....::..|
Zfish     7 LVGLWSLLSLSHAQLADTTDAEGEEEAVDLFTTPRTKLAAATSDFGYNLFRQLASRDTKASVFLS 71

  Fly    69 PFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDS-QILRIANKIFVMD 132
            |.||........:||......|:.:.|...:....|:..:...:|::.:.| :..:.|.:|.:..
Zfish    72 PMSISAAFTQLSMGASERAEKQIYRALRYHTLQDSQLHDTLRDLLSSLRASAKGFKSAERILLAR 136

  Fly   133 GYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLV 197
            ..:||.|:...:.||:....|.:  :...:...|:|:|.:|:|...:..:||:. |...:.|:.|
Zfish   137 KLRLRLEYLNSVEKQYGERPQIL--AGGARDLKTVNDWFKQQTGGKVDQVVPSP-LPRNTALLPV 198

  Fly   198 NAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDA----MALELPYKD 258
            .:.:|||.|..:|.|. .:.:||..||:....:|||   |:..|.....:|:    ...::|.:|
Zfish   199 GSAYFKGKWITRFGKP-NKMETFRRDGQAPAVIPMM---EQENYPVKMGIDSDLGCTIAQVPMED 259

  Fly   259 SDLSMLIVLPNTKT-GLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGM 322
            . :||...||:..| .|..:||.|....:..::.||:..||.|.||..|..::..|......||:
Zfish   260 G-VSMYFFLPDEVTQNLTLIEEALTAEFVQDLSNSLHTVKVLLTLPVIKLSYKTNLLPSLSDLGL 323

  Fly   323 SRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFA 387
            |...: :.:..|:  :.:|:|::|:.||..:|...||.|.|:.|..|..:...       :.:..
Zfish   324 SEWLA-ETDLTKI--TSQPVKLNAVHHKVVLETAPEGAEYASTTPSATGQSLG-------LSYRV 378

  Fly   388 DHPFTYVLVHQKDLP----LFWGSVV 409
            |.||.:::   :|.|    ||.|.|:
Zfish   379 DRPFLFLV---RDEPSGALLFIGKVL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	92/372 (25%)
serpinf1	NP_001004539.1	SERPIN	30..403	CDD:294093	94/393 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010