DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and Spn28Da

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	116/404 - (28%)
Similarity:	204/404 - (50%)	Gaps:	42/404 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CWLLPLLGLALFPFPPVHTADVTMADAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQT 74
            ||:|.             |..|             |..|:..:|..........||:.||..::.
  Fly     5 CWILV-------------TTSV-------------LGQFTKQLYRSFLQDNKQYNIIASPLCVEI 43

  Fly    75 CAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDSQ---ILRIANKIFVMDGYQL 136
            ..:|..:||:..||.:|...|.| ..|.:.:|..:.::|...:..:   ||.:||::||.:...:
  Fly    44 GMSMILMGADGNTANELRTALNL-PEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGV 107

  Fly   137 RQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKD-LVPADVLNSESRLVLVNAI 200
            .:.:::|::|.|.:.|:::..:..::||..||:||..:|...:|| ::|:|:...|| .|::||.
  Fly   108 NKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDES-AVMINAA 171

  Fly   201 HFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLI 265
            .|||.|:.:|.|..|:|..|::.....|.|.|||...||:.. ...:|.: :|||:..|:|||:|
  Fly   172 FFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFKMR-TSTIDQI-IELPFAYSNLSMVI 234

  Fly   266 VLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQA 330
            |||.....|...|..:.  :..||.  |.|..|.::||:||.:|::||.|..:.:|:..:|:..:
  Fly   235 VLPKDNGSLTQAEATIE--SYPQIV--LTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSS 295

  Fly   331 EFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVL 395
            :...:| :....::|.::||||||::|||..|.:|:...:|......:  ..:.|..:.||.: :
  Fly   296 DISVLL-NQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYAT--SVVTFTVNSPFVF-M 356

  Fly   396 VHQKDLPLFWGSVV 409
            :...|...|.|.||
  Fly   357 IRDDDNIYFRGRVV 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	109/366 (30%)
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	108/364 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446398
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	9	8.900