DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Da and serpina1l

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001013277.3	Gene:	serpina1l / 321195	ZFINID:	ZDB-GENE-040721-3	Length:	433	Species:	Danio rerio

Alignment Length:	391	Identity:	122/391 - (31%)
Similarity:	198/391 - (50%)	Gaps:	24/391 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PVHTADVTMADAAHQEFARRLALFSINVYGKLSG--QKPGENIVFSPFSIQTCAAMARLGAENET 87
            |.|..    .||.|. .|...|.|:.::|.||:.  ...|:||.|||..|....::..:||:..|
Zfish    55 PSHKG----VDACHL-LAPHNADFAFSLYKKLASNPDAQGKNIFFSPVGISMALSLLAVGAKGST 114

  Fly    88 ATQLDQGLGLASSDPEQI----AHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQF 148
            .:|:..|||.::..|||:    .|..| :|...||:..|.....:.:.||:::..:|.:.....:
Zfish   115 LSQIYSGLGYSALTPEQVNEGYEHLLH-MLGHSQDAMQLEAGAGVAIRDGFKVVDQFLKDAQHYY 178

  Fly   149 LSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKH 213
            .|.|..|||||...|||.||.::.::|:..|.::|..  |::::.::|:|.::|:|.|:.||...
Zfish   179 NSEAFGVDFSKPEIAAAEINKFIARKTHDKITNMVKD--LDADTVMMLINYMYFRGKWEKQFDAK 241

  Fly   214 LTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALE 278
            ||....|.:|.:.||||.||....|:.....|......|.:||| .:.||||||||... :..||
Zfish   242 LTHKADFKVDQDTTVQVDMMKRTGRYDIYQDPVNQTTVLMVPYK-GNTSMLIVLPNDGK-MKELE 304

  Fly   279 EKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLK 343
            |.:....|......|:.:.|.|.:|:|......:|.::...:||:..|..:|:|..|.:..: ::
Zfish   305 ESICRHHLKNWHDKLFRSSVDLFMPKFSISATSKLDDILMDMGMTDAFDYKADFSGMTEEVK-VR 368

  Fly   344 VSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQKDLP-LFWGS 407
            ||.::|:|.:.|:|:||||||.|.:      .||....|.....:.||..::|....:. ||.|.
Zfish   369 VSRVLHQAVMSVDEKGTEAAAITTI------EIMPMSLPHTVILNRPFLVLIVEDSTMSILFMGK 427

  Fly   408 V 408
            :
Zfish   428 I 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	116/369 (31%)
serpina1l	NP_001013277.3	alpha-1-antitrypsin_like	69..428	CDD:239011	116/370 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010