DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001100821.1	Gene:	Serpinb9d / 306890	RGDID:	1308725	Length:	337	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	109/339 - (32%)
Similarity:	185/339 - (54%)	Gaps:	17/339 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 MARLGAENETATQLDQGLGLASSDPEQIAHSFHQVLA----AYQDSQILRIANKIFVMDGYQLRQ 138
            |..|||:.:||.|:.|.|.| :..|::..|...|:|.    ..:....|||||::|..:..:|..
  Rat     1 MVLLGAKGDTAVQISQALNL-NKHPDEDIHKDFQLLLHNLNKPKSHYCLRIANRLFAENTCKLVP 64

  Fly   139 EFDQLLSKQFLSAAQSVDFSKNVQAAAT-INNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHF 202
            .:.:...:.:.|..:.:.|:|..:.:.. ||.||.::|...|.:|:.:|.:.||::|::|||::|
  Rat    65 TYKESCLRFYNSEIEQLSFAKAAEESRKHINTWVSKQTEGKIPELLSSDSVGSETKLIMVNALYF 129

  Fly   203 KGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVL 267
            :|:|.|.|.|..|....|.::.:.|..|.||..:|.|..|.:..:.|..|.:||:..::|.:::|
  Rat   130 QGSWLHCFDKEFTMEMPFKINKKETKPVQMMWQEETFDVAYVKEIQAQILVMPYRGMEMSFMVLL 194

  Fly   268 PNTKTGLPALEEKLRLTTLSQIT--QSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSD-Q 329
            |:....:..:|..|....|:..|  :.:|.|:|.:.||:|:.:.|.:::.:||.|||..:||: :
  Rat   195 PDEGVDIRKVESSLTFEKLTAWTKPEFIYSTEVYVYLPKFQLQEQYDMTALFQHLGMIDVFSEIK 259

  Fly   330 AEFGKMLQSPE-PLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTY 393
            |:...|  .|| .|.||..:|:..:||||||||||||:........:..:|    .|.||.||.:
  Rat   260 ADLSGM--CPEKDLCVSKFVHECVVEVNEEGTEAAAASAADCCYSCSEYTP----TFCADRPFLF 318

  Fly   394 VLVH-QKDLPLFWG 406
            .:.| |.:..||.|
  Rat   319 FIRHNQTNSILFCG 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	109/339 (32%)
Serpinb9d	NP_001100821.1	SERPIN	1..337	CDD:294093	109/339 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830