DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and Serping1

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	112/409 - (27%)
Similarity:	188/409 - (45%)	Gaps:	56/409 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LFPFPPVHTADVTMADAAHQEFARRLALFSINVYGKLSGQKPGE-NIVFSPFSIQTCAAMARLGA 83
            |.|.|....:| :..|::....:..|..||:.:|...|..|..| |:.||||||.:......|||
  Rat   127 LCPEPLAWCSD-SDRDSSEATLSEALTDFSVKLYHAFSATKKAETNMAFSPFSIASLLTQVLLGA 190

  Fly    84 ENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQF 148
            .:.|.:.|:..|    |.|:..| ..||.|.|:....:..::         |:....|..:...:
  Rat   191 GDSTKSNLEDIL----SYPKDFA-CVHQTLKAFSSKGVTSVS---------QIFHSPDLAIRDTY 241

  Fly   149 LSAAQSV----------DFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFK 203
            ::|:.|:          |...|::   .||.||.:.|||.|.:|:  |.|.|::||||:||::..
  Rat   242 VNASLSLYGSSPRVLGPDGDANLK---LINTWVAENTNHKINELL--DSLPSDTRLVLLNAVYLS 301

  Fly   204 GTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKE----RFRYADLPALDAMALELPYKDSDLSML 264
            ..|:..|.:........:.:.  .::|||:|.|:    .|....|.| ....|:|.:   :||.:
  Rat   302 AKWKKTFEQKKMMASFLYKNS--MIKVPMLSSKKYPLALFNDQTLKA-KVGQLQLSH---NLSFV 360

  Fly   265 IVLPNTKT-GLPALEEKLRLTTLSQITQSLYETK---VALKLPRFKAEFQVELSEVFQKLGMSRM 325
            |::|.:.| .|..:|:.|..|....|.:.|..:|   ..:.:||.|.:...::..:.:||.....
  Rat   361 IMVPQSPTHQLEDMEKALNPTVFKAILKKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKLEFFDF 425

  Fly   326 FSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHP 390
            ..|....| :.:.|: |:||::.|:..:|:.|.|.|||||:.::|.|...|        |....|
  Rat   426 TYDLNLCG-LTEDPD-LQVSSMKHETVLELTETGVEAAAASTISVARNLLI--------FEVQQP 480

  Fly   391 FTYVLVHQK-DLPLFWGSV 408
            |.::|..|: ..|:|.|.|
  Rat   481 FLFLLWDQRHKFPVFMGRV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	106/382 (28%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132		2/4 (50%)
		SERPIN	150..499	CDD:294093	106/383 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010