Protein Alignment Spn42Da and Serpina3b

DIOPT Version :10

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_766612.1
• Gene: Serpina3b / 271047
• MGIID: 2182835
• Length: 420
• Species: Mus musculus
• Alignment Length: 387
• Identity: 110/387 - (28%)
• Similarity: 181/387 - (46%)
• Gaps: 30/387 - (7%)

  Fly    45 LALFSINV------YGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGL--GLASSD 101
            |.|.|||.      |.:|:.:.|.:||.||||.|.|......|||:..|..::.:.|  .|..:.
Mouse    45 LTLASINTDFAFSFYKELALKNPHKNIAFSPFGIATALNSLTLGAKGNTLEEILEVLKFNLTETS 109

  Fly   102 PEQIAHSFHQVL--AAYQDSQI-LRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQA 163
            ...|...|..:|  .::...|: :|..|.:||....|:..||.:.....:.:...:.:|.:..:|
Mouse   110 EADIHQGFKHLLQRLSHPGDQVQIRTGNALFVEKHLQILAEFKEKARALYHTEVFTANFQQPHEA 174

  Fly   164 AATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTV 228
            ...||:::..:|...||:|| :| ::..:.:|:||.:.||..|...|....|....|.:|..|.|
Mouse   175 MKLINSYMSNQTQGKIKELV-SD-MDGNTSMVIVNDLFFKAEWMVPFNSDDTFMGKFIVDRSRHV 237

  Fly   229 QVPMMSLKE-RFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQS 292
            :||||..|. |..|.....|....:||.||.:..:|.|:....|  :..:|..|:..||.:..:|
Mouse   238 KVPMMKTKNLRTPYFRDEELKCTVVELNYKGNGKAMFILPDQGK--MQQVEASLQPGTLKKWRKS 300

  Fly   293 LYETKV-ALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVN 356
            |...|: .|.||:|.......|.::..:||:..:||.||:... :...:.:.||.:||...:::.
Mouse   301 LRPRKIKELHLPKFSLSQHYNLEDILPELGIRELFSTQADLSG-ITGVKNITVSEMIHSTELDMT 364

  Fly   357 EEGTEAAAATGMAVRRKRAIMSPE-EPIEFFADHPFTYVLVHQKDLPLFW----GSVVRLEE 413
            |:|||..|.|.:...    .||.: :|:....:..|.|:::.|.||   |    |.|:...|
Mouse   365 EKGTEGDAITIVGYN----FMSAKLKPVFVKFEDQFLYIVLDQGDL---WIHVMGKVINPSE 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	107/379 (28%)
Serpina3b	NP_766612.1	serpinA3_A1AC	37..418	CDD:381019	109/384 (28%)
		RCL	367..392		8/28 (29%)