Protein Alignment Spn42Da and Serpine2

DIOPT Version :10

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_033281.1
• Gene: Serpine2 / 20720
• MGIID: 101780
• Length: 397
• Species: Mus musculus
• Alignment Length: 404
• Identity: 123/404 - (30%)
• Similarity: 207/404 - (51%)
• Gaps: 30/404 - (7%)

  Fly    21 FPFPPVHTADVTMADAAHQEFARRLAL------FSINVYGKLSGQKPGENIVFSPFSIQTCAAMA 79
            |||..:.|  ||:. :.|.:| ..|:|      ..|.|:.::...:|.||:|.||..|.:...|.
Mouse     5 FPFFILTT--VTLY-SVHSQF-NSLSLEELGSNTGIQVFNQIIKSRPHENVVVSPHGIASILGML 65

  Fly    80 RLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLL 144
            :|||:.:|..||...:....:...::....::.:.:.::..|:.:||.:|:.:|:::...|....
Mouse    66 QLGADGKTKKQLSTVMRYNVNGVGKVLKKINKAIVSKKNKDIVTVANAVFLRNGFKMEVPFAVRN 130

  Fly   145 SKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSE-SRLVLVNAIHFKGTWQH 208
            ...|....|:|:|.....|:.:||.||:..|..:|.:|:..::::.. :|||||||::|||.|:.
Mouse   131 KDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWKS 195

  Fly   209 QFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAM---ALELPYKDSDLSMLIVLP-N 269
            :|....|:..||.....::.||||::....||.......:.:   .:||||....:||||.|| .
Mouse   196 RFQPESTKKRTFVAGDGKSYQVPMLAQLSVFRSGSTRTPNGLWYNFIELPYHGESISMLIALPTE 260

  Fly   270 TKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFG 333
            :.|.|.|:...:...|:.....::...::.|.||:|.|..|.:|.|..:.||::.||. .:|.|.
Mouse   261 SSTPLSAIIPHITTKTIDSWMNTMVPKRMQLVLPKFTAVAQTDLKEPLKALGITEMFEPSKANFT 325

  Fly   334 KMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQ 398
            |:.:| |.|.||.|:.||.|||:|:||:|:|||      ...:::...|..|..|.||.:.:.|.
Mouse   326 KITRS-ESLHVSHILQKAKIEVSEDGTKASAAT------TAILIARSSPPWFIVDRPFLFSIRHN 383

  Fly   399 KDLP----LFWGSV 408
               |    ||.|.|
Mouse   384 ---PTGAILFLGQV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	113/377 (30%)
Serpine2	NP_033281.1	serpinE2_GDN	21..395	CDD:381039	116/385 (30%)