DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Da and Serpine2

DIOPT Version :9

Sequence 1:	NP_524955.2	Gene:	Spn42Da / 49805	FlyBaseID:	FBgn0265137	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_033281.1	Gene:	Serpine2 / 20720	MGIID:	101780	Length:	397	Species:	Mus musculus

Alignment Length:	404	Identity:	123/404 - (30%)
Similarity:	207/404 - (51%)	Gaps:	30/404 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FPFPPVHTADVTMADAAHQEFARRLAL------FSINVYGKLSGQKPGENIVFSPFSIQTCAAMA 79
            |||..:.|  ||:. :.|.:| ..|:|      ..|.|:.::...:|.||:|.||..|.:...|.
Mouse     5 FPFFILTT--VTLY-SVHSQF-NSLSLEELGSNTGIQVFNQIIKSRPHENVVVSPHGIASILGML 65

  Fly    80 RLGAENETATQLDQGLGLASSDPEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLL 144
            :|||:.:|..||...:....:...::....::.:.:.::..|:.:||.:|:.:|:::...|....
Mouse    66 QLGADGKTKKQLSTVMRYNVNGVGKVLKKINKAIVSKKNKDIVTVANAVFLRNGFKMEVPFAVRN 130

  Fly   145 SKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSE-SRLVLVNAIHFKGTWQH 208
            ...|....|:|:|.....|:.:||.||:..|..:|.:|:..::::.. :|||||||::|||.|:.
Mouse   131 KDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWKS 195

  Fly   209 QFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAM---ALELPYKDSDLSMLIVLP-N 269
            :|....|:..||.....::.||||::....||.......:.:   .:||||....:||||.|| .
Mouse   196 RFQPESTKKRTFVAGDGKSYQVPMLAQLSVFRSGSTRTPNGLWYNFIELPYHGESISMLIALPTE 260

  Fly   270 TKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFG 333
            :.|.|.|:...:...|:.....::...::.|.||:|.|..|.:|.|..:.||::.||. .:|.|.
Mouse   261 SSTPLSAIIPHITTKTIDSWMNTMVPKRMQLVLPKFTAVAQTDLKEPLKALGITEMFEPSKANFT 325

  Fly   334 KMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQ 398
            |:.:| |.|.||.|:.||.|||:|:||:|:|||      ...:::...|..|..|.||.:.:.|.
Mouse   326 KITRS-ESLHVSHILQKAKIEVSEDGTKASAAT------TAILIARSSPPWFIVDRPFLFSIRHN 383

  Fly   399 KDLP----LFWGSV 408
               |    ||.|.|
Mouse   384 ---PTGAILFLGQV 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	114/378 (30%)
Serpine2	NP_033281.1	serpinE2_GDN	21..395	CDD:381039	116/385 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11110
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030