Protein Alignment Spn42Da and SERPINB1

DIOPT Version :9

• Sequence 1: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_109591.1
• Gene: SERPINB1 / 1992
• HGNCID: 3311
• Length: 379
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 138/377 - (36%)
• Similarity: 206/377 - (54%)
• Gaps: 27/377 - (7%)

  Fly    48 FSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQV 112
            |:::::..||...|..||..|||||.:..||..||....||.||.:....  :..|:: ||..|.
Human    11 FALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF--NTVEEV-HSRFQS 72

  Fly   113 LAAYQD----SQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFS-KNVQAAATINNWVE 172
            |.|..:    |.||::||:::....|....||.....|.:.:...||||. .:..|..|||.||:
Human    73 LNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVK 137

  Fly   173 QRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKE 237
            .:|...|.:|:.:.::::.::|||||||:|||.|:.:|.|..|....|.|:.:....|.||..|:
Human   138 GQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKK 202

  Fly   238 RFRYADLPALDAMALELPYKDSDLSMLIVLP----NTKTGLPALEEKLRLTTLSQIT--QSLYET 296
            :|.|..:..|....|||||:..:|||:|:||    :..|||..:||:|.|..|.:.|  ::|...
Human   203 KFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFI 267

  Fly   297 KVALKLPRFKAEFQVELSEVFQKLGMSRMF-SDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGT 360
            :|.:.|||||.|....|:....:||:..:| |.:|:...| .....:.:|.|:||:|:|||||||
Human   268 EVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGM-SGARDIFISKIVHKSFVEVNEEGT 331

  Fly   361 EAAAAT-GMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQKDLPLFWGSVVRL 411
            |||||| |:|.   ..::.|||  .|.|||||.:.:.|...     ||::.|
Human   332 EAAAATAGIAT---FCMLMPEE--NFTADHPFLFFIRHNSS-----GSILFL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Da	NP_524955.2	SERPIN	45..408	CDD:238101	136/372 (37%)
SERPINB1	NP_109591.1	SERPIN	4..379	CDD:294093	138/377 (37%)
		CARD-binding motif (CBM). /evidence=ECO:0000269|PubMed:30692621	351..379		10/28 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.830