Protein Alignment Spn88Ea and SERPINB12

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 121/443 - (27%)
• Similarity: 194/443 - (43%)
• Gaps: 85/443 - (19%)

  Fly    35 NLYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKE 99
            :|......|...:...|.:...::|:||||.|...||.:...|:..|:..::.:|||.:.....|
Human    15 SLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNE 79

  Fly   100 VVRSAYILEKMNRK---------ERQSKMPLE--------------------FSSADRIFFANDL 135
            .......|:...:|         ::::..||:                    .|..|||.....|
Human    80 SKEPDPCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYTL 144

  Fly   136 HVTECARNRLAEE--------------------VQQIDFKSQTEESRKQINDWIAKQTHDQIRNM 180
            .:.    |||..|                    ::.:||:...|:||::||.|:..|:..:|:.:
Human   145 SIA----NRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKEL 205

  Fly   181 LSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQL 245
            .|.|.|...|.|||.||.|.|.:|.:.|..|.||..||..:.:....|.||.|||.:.:...|::
Human   206 FSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEV 270

  Fly   246 RAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPF---NSNSLEDVLSRLNADSLD--DSLK 305
            :|.:|::.|               ....:||.::||..   |...||::..::..:.:.  .|.:
Human   271 KAQILEMRY---------------TKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSE 320

  Fly   306 QAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLT----SETISIGDSKHVAKI 366
            ......:.:|.|:|..|...:||.||..||::.:|||:.|   |||    |..:.:....|...:
Human   321 NMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRA---DLTGISPSPNLYLSKIIHKTFV 382

  Fly   367 KVDEEGSTAAAAT-VLFTYRSARP-VEPAKFECNHPFLFVIYDRTSRSILFTG 417
            :|||.|:.||||| .:.:.||.|. ||   |..||||||.|....:::|||.|
Human   383 EVDENGTQAAAATGAVVSERSLRSWVE---FNANHPFLFFIRHNKTQTILFYG 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	120/439 (27%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	121/442 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820