DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Ea and SERPIN1

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001320925.1	Gene:	SERPIN1 / 841182	AraportID:	AT1G47710	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	110/441 - (24%)
Similarity:	184/441 - (41%)	Gaps:	47/441 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 HILSISLMAVLPAIALAGLCGVEPDAGLLDQRLNLYKGQQ---NFAVSMLNVIRQSTPNENVFFS 63
            |:|.::|..|...:..:.  ..:|.| .:|.|.::....|   |.|..::..:.|   |.||.||
plant     3 HLLRLALRRVRKFVYQSS--PPQPPA-KMDVRESISLQNQVSMNLAKHVITTVSQ---NSNVIFS 61

  Fly    64 PYSTYHALLLAYFGSSGDTEKELAKVLHLDWAD-----SKEVVRSAYILEKMNRKERQSKMPLEF 123
            |.|....|.:...||:|.|:.::...|.....|     |.|:|.:.......|...:       .
plant    62 PASINVVLSIIAAGSAGATKDQILSFLKFSSTDQLNSFSSEIVSAVLADGSANGGPK-------L 119

  Fly   124 SSADRIFFANDLHVTECARNRLAEEVQ----QIDFKSQTEESRKQINDWIAKQTHDQIRNMLSAD 184
            |.|:..:....|......:..|.:..:    |.||:|:..|...::|.|..|:|:..|..:|...
plant   120 SVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEVNSWAEKETNGLITEVLPEG 184

  Fly   185 EITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHV 249
            .....|:|:.|||.|.||.|..:|....|....|:....|......|..|....::..:..:  |
plant   185 SADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNKVTAPFMTSKKKQYVSAYDGFK--V 247

  Fly   250 LQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRL--NADSLDDSLKQAMPREI 312
            |.|||   .:.|:|.        ..||...||..| |.|.|:|.::  ....||:.:.:...:..
plant   248 LGLPY---LQGQDKR--------QFSMYFYLPDAN-NGLSDLLDKIVSTPGFLDNHIPRRQVKVR 300

  Fly   313 EVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTS----ETISIGDSKHVAKIKVDEEGS 373
            |..:|||:|....:.:.:|..:|::..|.......:.:.|    :.:.:.:..|.|.|:|:|||:
plant   301 EFKIPKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGT 365

  Fly   374 TAAAAT--VLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            .||||:  |:.........:...|..:||||.|:.:..:..:||.|...||
plant   366 EAAAASAGVIKLRGLLMEEDEIDFVADHPFLLVVTENITGVVLFIGQVVDP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	100/399 (25%)
SERPIN1	NP_001320925.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010