Protein Alignment Spn88Ea and Serpina12

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 442
• Identity: 115/442 - (26%)
• Similarity: 204/442 - (46%)
• Gaps: 77/442 - (17%)

  Fly    17 LAGLCGVEPDAGLLDQ-----------RLNLYKGQQN----------FAVSMLNVIRQSTPNENV 60
            ||||..|:   |||..           |:..::|:::          |...:|..:..::|..|:
Mouse    11 LAGLLTVK---GLLQDRDAPDMYDSPVRVQEWRGKKDARQLARHNMEFGFKLLQRLASNSPQGNI 72

  Fly    61 FFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV----VRSA--YILEKMNRKERQSKM 119
            |.||.|...|..:...|:...|.:|:.:..:.     ||:    |.:|  |:|.|:|::...:||
Mouse    73 FLSPLSISTAFSMLSLGAQNSTLEEIREGFNF-----KEMSNWDVHAAFHYLLHKLNQETEDTKM 132

  Fly   120 PLEFSSADRIFFANDLHVTECARNRLAEEVQQIDFK----SQTEESRKQINDWIAKQTHDQIRNM 180
            .|    .:.:|....|...:...| ||:.|...|..    ...|.::|.||.:|:::||.:|:||
Mouse   133 NL----GNALFMDQKLRPQQRFLN-LAKNVYDADMVLTNFQDLENTQKDINRYISQKTHSRIKNM 192

  Fly   181 LSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQL 245
            :.:  |.|.|.::|.|..|.:|:|..:|..::|....|:........|.||.|:|.:.:..|.||
Mouse   193 VKS--IDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVKVPMMFQRGLYDMAYDSQL 255

  Fly   246 RAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPR 310
            ...:|::|||                .:|:...:||  ::..|:.:...|.||...........|
Mouse   256 SCTILEIPYR----------------GNITATFVLP--DNGKLKLLEQGLQADIFAKWKSLLSKR 302

  Fly   311 EIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLT----SETISIGDSKHVAKIKVDEE 371
            .::|.:||........:..:|:::|:||:|:|:    .|||    ..::.:|::.|.|::|:||:
Mouse   303 VVDVWVPKLRISSTYNMKKVLSRLGISKIFEEN----GDLTRISSHRSLKVGEAVHKAELKMDEK 363

  Fly   372 GSTAAAATVLFTYRSARPVE-PAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            |...||.:...|.    |:| |...:.:.|||.:||:....|::|.....||
Mouse   364 GMEGAAGSGAQTL----PMETPRHMKLDRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	104/404 (26%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	103/394 (26%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010