Protein Alignment Spn88Ea and SERPINB3

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 123/409 - (30%)
• Similarity: 199/409 - (48%)
• Gaps: 42/409 - (10%)

  Fly    35 NLYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKE 99
            :|.:....|...:....|:|..| |:|:||.|...||.:...|:..:|.:::.||||.|......
Human     3 SLSEANTKFMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENT 66

  Fly   100 VVRSA-YILEKMNRKERQ-SKMPLEF---SSADRIFFANDL----------HVTECARNRLAEEV 149
            ..::| |.:::......| .|:..||   :.|..:..||.|          ...:..:......|
Human    67 TGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSV 131

  Fly   150 QQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTV 214
            :.:||.:..|||||:||.|:..||:::|:|::....|...|.|||.||.|.||||..:|..|.|.
Human   132 ESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTK 196

  Fly   215 PMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLI 279
            ...|:.:.:.|..:.||:|..:|.....|.::|.||::||:               ..|:||:::
Human   197 EEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYK---------------GKDLSMIVL 246

  Fly   280 LPPFNSNSLEDVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDE 342
            ||. ..:.|:.:..:|.|:.|.:  ||:......:::.||:|:.|:..:|...|..||:..:|:.
Human   247 LPN-EIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNG 310

  Fly   343 SVATFDDLTSETISIG----DSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLF 403
            ..    ||:..|.|.|    ...|.|.::|.|||:.|||||.:..:.|:......:|.|||||||
Human   311 DA----DLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLF 371

  Fly   404 VIYDRTSRSILFTGIYRDP 422
            .|....:.||||.|.:..|
Human   372 FIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	121/400 (30%)
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	122/407 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820