Protein Alignment Spn88Ea and SERPINI2

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001012303.2
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 106/425 - (24%)
• Similarity: 189/425 - (44%)
• Gaps: 74/425 - (17%)

  Fly    34 LNLYKGQQ----------NFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAK 88
            |.|:.|.|          .|||.:...:..| ..:|:.|||......|.:...|:.|..::::.:
Human    10 LLLFFGSQASRCSAQKNTEFAVDLYQEVSLS-HKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQ 73

  Fly    89 VLHLDWADSKEVVRSA----YILEKMNRKERQSKMPLEFSSADRIFFANDLHVTE----CARNRL 145
            .|       |:...||    ::|:.......:.|....|:.|:.::......|.|    ..:...
Human    74 TL-------KQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFF 131

  Fly   146 AEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKT 210
            ...::.:||: ..:...:.|:.|:.::|..:|::|.|.:|..|.|||||.||.|.||.|..:|:.
Human   132 QSAIKLVDFQ-DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRK 195

  Fly   211 EKTVPMPFYTSPSNYSLVSMMQQKGTFLLNV------DEQLRAHVLQLPYRTVFESQEKEDSSPD 269
            |.|..:.|  :..|.|.|.:...|.  ||..      :..|...||:|.|:
Human   196 EDTQLINF--TKKNGSTVKIPMMKA--LLRTKYGYFSESSLNYQVLELSYK-------------- 242

  Fly   270 ENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKM 334
             ..:.|:::|||. ....:|:|...:.|..:...|.:....|:|:|||:|:.||:::...:|..:
Human   243 -GDEFSLIIILPA-EGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSL 305

  Fly   335 GVSKMFDESVATFDDLTSETISIGDSKHVAKI------KVDEEGSTAAAATVLFTYRSARPV--- 390
            .::::|....    ||:..|.|  ...:|:::      :::|:||.||.:|.:..     ||
Human   306 NITEIFSGGC----DLSGITDS--SEVYVSQVTQKVFFEINEDGSEAATSTGIHI-----PVIMS 359

  Fly   391 -EPAKFECNHPFLFVIYDRTSRSILFTGIYRDPKT 424
             ..::|..||||||::....:.||||.|...:|.|
Human   360 LAQSQFIANHPFLFIMKHNPTESILFMGRVTNPDT 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	102/413 (25%)
SERPINI2	NP_001012303.2	serpinI2_pancpin	23..392	CDD:381042	100/408 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020