Protein Alignment Spn88Ea and SERPINB2

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 121/426 - (28%)
• Similarity: 198/426 - (46%)
• Gaps: 67/426 - (15%)

  Fly    43 FAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVV------ 101
            ||:::...:.:::|.:|:|.||:|....:.:.|.||.|.||.::||||..:...:..|.
Human    11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPEN 75

  Fly   102 -RSAYILEKMNRKERQSKMPLEFSSADRI---FFANDLHVTECARNRLAEEV------------- 149
             .|...::::.:......: |:..:||:|   |.:....:.....|.|.|.|
Human    76 FTSCGFMQQIQKGSYPDAI-LQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFRE 139

  Fly   150 --------------QQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYL 200
                          |.:||....||:||:||.|:..||..:|.|:|....:...||:||.||.|.
Human   140 EYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYF 204

  Fly   201 KGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKED 265
            ||:|.:.|:.:.....||..:.:..:.|.||..:....:...|.|:|.:|:|||.
Human   205 KGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYA---------- 259

  Fly   266 SSPDENSDISMVLILP---PFNSNSLEDVLSRLNADSLDD-SLKQAMPR-EIEVSLPKFEFEQRL 325
                  .|:||.|:||   ...|..||.:.|.:..|.|:. :.|..|.. |:||.:|:|:.|:..
Human   260 ------GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHY 318

  Fly   326 ELNPILAKMGVSKMFDESVATFDDLTSET-ISIGDSKHVAKIKVDEEGSTAAAAT-VLFTYRSAR 388
            ||..||..||:...|::..|.|..::... :.:.:..|.|.:.|:|||:.|||.| .:.|.|:..
Human   319 ELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGH 383

  Fly   389 --PVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
              |    :|..:|||||:|..:.:..|||.|.:..|
Human   384 GGP----QFVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	120/421 (29%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	120/424 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920