Protein Alignment Spn88Ea and SERPINE1

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 104/384 - (27%)
• Similarity: 169/384 - (44%)
• Gaps: 55/384 - (14%)

  Fly    42 NFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKEL--AKVLHLDWADSKEVVRSA 104
            :|.|.:...:.|::.:.||.||||.....|.:....:.|:|::::  |....:|.......:|..
Human    37 DFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHL 101

  Fly   105 Y--ILEKMNRKERQSKMPLEFSSADRIFFANDL--------HVTECARNRLAEEVQQIDFKSQTE 159
            |  ::...|:.        |.|:.|.||...||        |.....|:    .|:|:|| |:.|
Human   102 YKELMGPWNKD--------EISTTDAIFVQRDLKLVQGFMPHFFRLFRS----TVKQVDF-SEVE 153

  Fly   160 ESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSN 224
            .:|..||||:...|...|.|:|....:...|||||.||.|..|||.:.|....|....|:.|..:
Human   154 RARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGS 218

  Fly   225 YSLVSMMQQKGTFLLNVDEQLRAH---VLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNS- 285
            ...|.||.|...|..........|   :|:|||                :.|...:.|..|:..
Human   219 TVSVPMMAQTNKFNYTEFTTPDGHYYDILELPY----------------HGDTLSMFIAAPYEKE 267

  Fly   286 ---NSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATF 347
               ::|.::||.........::.: :||.:  .||||..|..::|...|..:|::.||.:..|.|
Human   268 VPLSALTNILSAQLISHWKGNMTR-LPRLL--VLPKFSLETEVDLRKPLENLGMTDMFRQFQADF 329

  Fly   348 DDLT-SETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVI 405
            ..|: .|.:.:..:....||:|:|.|:.|:::|.:..  ||| :.|.:...:.|||||:
Human   330 TSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIV--SAR-MAPEEIIMDRPFLFVV 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	104/384 (27%)
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	104/384 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020