Protein Alignment Spn88Ea and SERPINC1

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 129/508 - (25%)
• Similarity: 205/508 - (40%)
• Gaps: 107/508 - (21%)

  Fly     1 MHILSISLMAVLPAIALAG----LCGVEP--------------------DAGLLDQRL------- 34
            :::||:.|:.....:...|    :|..:|                    |.| .:|::
Human    16 VYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEG-SEQKIPEATNRR 79

  Fly    35 --NLYKGQQNFAVSMLNVIRQS-TPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWAD 96
              .|.|....||.:....:..| ..|:|:|.||.|...|..:...|:..||.::|.:|...|...
Human    80 VWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTIS 144

  Fly    97 SKEVVRSAYILEKMN-RKERQSKMPLEFSSADRIFFANDLHVTECARNRLAE-----EVQQIDFK 155
            .|...:..:...|:| |..|::....:..||:|:|....|...|..:: ::|     ::|.:|||
Human   145 EKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQD-ISELVYGAKLQPLDFK 208

  Fly   156 SQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLK------------------- 201
            ...|:||..||.|::.:|..:|.:::.::.|...|.|||.|..|.|
Human   209 ENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLT 273

  Fly   202 ----------------------GQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTF-LLNVDE 243
                                  |.|.|:|..|.|....||.:.......|||.|:|.| ...|.|
Human   274 PFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE 338

  Fly   244 QLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAM 308
              ...||:||::               ..||:||||||. ...||..|...|..:.|.:.|.:..
Human   339 --GTQVLELPFK---------------GDDITMVLILPK-PEKSLAKVEKELTPEVLQEWLDELE 385

  Fly   309 PREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSE---TISIGDSKHVAKIKVDE 370
            ...:.|.:|:|..|....|...|..||:..:|....:....:.:|   .:.:.|:.|.|.::|:|
Human   386 EMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNE 450

  Fly   371 EGSTAAAAT-VLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            |||.|||:| |:...||..| ....|:.|.|||..|.:....:|:|.|...:|
Human   451 EGSEAAASTAVVIAGRSLNP-NRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	117/432 (27%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	121/453 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020