Protein Alignment Spn88Ea and SERPINA2

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 97/454 - (21%)
• Similarity: 182/454 - (40%)
• Gaps: 91/454 - (20%)

  Fly    15 IALAGLCGVEPDAGLLD------QRLNLYKGQQ----------------NFAVSMLNVIRQSTPN 57
            :.|||||.:.|.:.:.|      |:.:.....|                :.|..:...:...:..
Human    10 LLLAGLCCLVPSSLVEDPQEDAAQKTDTSHHDQGDWEDLACQKISYNVTDLAFDLYKELADLSQT 74

  Fly    58 ENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV-VRSAY--ILEKMNRKERQSKM 119
            .||..:|.|...|..:...|:..||..|:.:.|:::..::.|. :...:  :|:.::|.:.:
Human    75 SNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVLQALSRPDTR--- 136

  Fly   120 PLEFSSADRIFFANDLHVT----ECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNM 180
             |:.::...:|....:.:.    |..:.....|...|:|: .|||:::|||:::.|:|..::.::
Human   137 -LQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFR-DTEEAKEQINNYVEKRTGRKVVDL 199

  Fly   181 LSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQL 245
            :.  .:...|.|.|.:.....|:|..:||.|..:...|:........|.|:...|.|.::.|.:|
Human   200 VK--HLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMINHLGRFDIHRDREL 262

  Fly   246 RAHVLQLPY---RTVFESQEKEDSSPDENSDISMVLILP-PFNSNSLEDVLSRLNADSLDDSLKQ 306
            .:.||...|   .|.|                   .||| |.....||:   :|....|::..:.
Human   263 SSWVLAQHYVGNATAF-------------------FILPDPKKMWQLEE---KLTYSHLENIQRA 305

  Fly   307 AMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSET-ISIGDSKHVAKIKVDE 370
            ...|.|.:..||.......:|..:|..:|::|:|... |....::.|. :.:..:.|||.:.:||
Human   306 FDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNE-ADLSGVSQEAPLKLSKAVHVAVLTIDE 369

  Fly   371 EGSTAAAA------------TVLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            :|:.|..|            ||:|               |.|||.:|.|..:...||.|...:|
Human   370 KGTEATGAPHLEEKAWSKYQTVMF---------------NRPFLVIIKDDITNFPLFIGKVVNP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	88/419 (21%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	86/400 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010