DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Ea and Serpinb3c

DIOPT Version :9

Sequence 1:NP_524954.2 Gene:Spn88Ea / 49804 FlyBaseID:FBgn0028984 Length:427 Species:Drosophila melanogaster
Sequence 2:NP_958751.2 Gene:Serpinb3c / 381286 MGIID:1277952 Length:386 Species:Mus musculus


Alignment Length:399 Identity:109/399 - (27%)
Similarity:199/399 - (49%) Gaps:42/399 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 FAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVVRSAYIL 107
            |.|.|...:|:|  ::|:|:||.|...||.:...|:.|:||.::.|||..:....|...:||:..
Mouse    11 FTVEMYRQLRES--DKNIFYSPISMITALGMLKLGAKGNTEIQIEKVLQCNETTEKTTEKSAHCD 73

  Fly   108 EKMNRKERQSKM---------PLEFSSADRIFFANDLHVTECARNRLAE----EVQQIDFKSQTE 159
            ::.|..|:..|:         ..:..:|:.|:.|....:.:.....:.|    .|:.:||:...|
Mouse    74 DEDNVHEQFQKLITQLNKSNDDYDLKAANSIYGAKGFPLLQTFLEDIKEYYHANVESLDFEHAAE 138

  Fly   160 ESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSN 224
            ||.|:||.|:..:|:.:|:::..:..::..|:|||.||.|.||:|..:|....|:...|:.:.:.
Mouse   139 ESEKKINFWVKNETNGKIKDLFPSGSLSSSTKLVLVNAVYFKGRWNHKFDENNTIEEMFWLNKNT 203

  Fly   225 YSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLE 289
            ...|.||:|:..|:.:..|.::|.::::||:               ..::||.::| |...:.|:
Mouse   204 SIPVPMMKQRNKFMFSFLEDVQAQIVEIPYK---------------GKELSMFVLL-PMEIDGLK 252

  Fly   290 DVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTS 352
            .:..:|.|..|.:  ..:.....|:.:.||:|:.|::.:|...|..||:...||...|.|..::|
Mouse   253 QLEKQLTAAKLLEWTRAENMHLTELYLWLPRFKVEEKYDLPVPLECMGMVNAFDPQKADFSGMSS 317

  Fly   353 -ETISIGDSKHVAKIKVDEEGSTAAAAT---VLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSI 413
             :.:.:....|.:.::|:|||:.|..|:   |:.     |..:.|.|.|:|||||.|....:.||
Mouse   318 TQGLVVSKVLHKSFVEVNEEGTEADPASGEEVIL-----RLAQVADFRCDHPFLFFIIHSKTNSI 377

  Fly   414 LFTGIYRDP 422
            ||.|....|
Mouse   378 LFFGRISSP 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EaNP_524954.2 SERPIN 39..419 CDD:238101 108/394 (27%)
Serpinb3cNP_958751.2 SERPIN 6..386 CDD:294093 108/397 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BBFJ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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