DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and serpinc1

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_878283.1	Gene:	serpinc1 / 321545	ZFINID:	ZDB-GENE-030131-264	Length:	450	Species:	Danio rerio

Alignment Length:	401	Identity:	120/401 - (29%)
Similarity:	192/401 - (47%)	Gaps:	34/401 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LYKGQQNFAVSMLNVIRQSTPN-ENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKE 99
            |.|....||:|:...:.:...| ||:|.||.|...|..:...|:...|.::|.||...|....|.
Zfish    66 LSKANSRFALSLFKQLAEGKSNDENIFLSPISISTAFAMTKLGACNTTLEQLMKVFQFDTIKEKT 130

  Fly   100 VVRSAYILEKMN-RKERQSKMPLEFSSADRIFFANDL-------HVTECARNRLAEEVQQIDFKS 156
            ..:..:...|:| |..|:.....|..||:|:|.....       |::|..   ...::..:|||.
Zfish   131 SDQVHFFFAKLNCRLYRKKHETTELISANRLFGDKSTTFNETFQHISETV---YGAKLMPLDFKE 192

  Fly   157 QTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTS 221
            :.|.||..||:|||.:|.::|::.|....|...|.|||.||.|.||||.::|..:..:.:.|:.|
Zfish   193 KPEASRITINEWIANKTENRIKDTLPEGSIDTNTILVLVNAIYFKGQWKNKFDKQNVMKLDFHVS 257

  Fly   222 PSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSN 286
            |::...|.||.|:..|......:.:..:|:|||               ...||:||||| |....
Zfish   258 PTHKCPVPMMYQEKKFQYAKIPEDKVKILELPY---------------NGGDITMVLIL-PIEGA 306

  Fly   287 SLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLT 351
            :|.:|::.:|...|...|.......:.|.:|:|..|....|...|.|||:..:|..:.|:...:.
Zfish   307 TLSEVVANMNLKKLVGWLHAMKETTVAVQIPRFRVEDSFSLKEQLTKMGLEDLFSPANASLPGMV 371

  Fly   352 SE----TISIGDSKHVAKIKVDEEGSTAAAAT-VLFTYRSARPVEPAKFECNHPFLFVIYDRTSR 411
            ::    .:.|.|:.|.|.::|:||||.|:||| |:.|.||.. :...:|..:.|||..|.:.:..
Zfish   372 ADAEGPNLFISDAYHKAFLEVNEEGSEASAATAVVATGRSLN-IFREQFVADRPFLLFIRESSIN 435

  Fly   412 SILFTGIYRDP 422
            :::|||...:|
Zfish   436 ALIFTGRVANP 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	117/393 (30%)
serpinc1	NP_878283.1	antithrombin-III_like	62..443	CDD:239000	119/396 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020