DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001100821.1	Gene:	Serpinb9d / 306890	RGDID:	1308725	Length:	337	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	100/361 - (27%)
Similarity:	173/361 - (47%)	Gaps:	35/361 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LAYFGSSGDTEKELAKVLHLDWADSKEVVRS-AYILEKMNRKERQSKMPLEFSSADRIFFANDLH 136
            :...|:.|||..::::.|:|:....:::.:. ..:|..:|:.:....:.:    |:|:|..|...
  Rat     1 MVLLGAKGDTAVQISQALNLNKHPDEDIHKDFQLLLHNLNKPKSHYCLRI----ANRLFAENTCK 61

  Fly   137 VT-----ECAR--NRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVL 194
            :.     .|.|  |   .|::|:.|....|||||.||.|::|||..:|..:||:|.:...|:|::
  Rat    62 LVPTYKESCLRFYN---SEIEQLSFAKAAEESRKHINTWVSKQTEGKIPELLSSDSVGSETKLIM 123

  Fly   195 ANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFE 259
            .||.|.:|.||..|..|.|:.|||..:......|.||.|:.||.:...::::|.:|.:|||
  Rat   124 VNALYFQGSWLHCFDKEFTMEMPFKINKKETKPVQMMWQEETFDVAYVKEIQAQILVMPYR---- 184

  Fly   260 SQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAM--PREIEVSLPKFEFE 322
                       ..::|.:::||. ....:..|.|.|..:.|....|...  ..|:.|.||||:.:
  Rat   185 -----------GMEMSFMVLLPD-EGVDIRKVESSLTFEKLTAWTKPEFIYSTEVYVYLPKFQLQ 237

  Fly   323 QRLELNPILAKMGVSKMFDESVATFDDLTSE-TISIGDSKHVAKIKVDEEGSTAAAATVLFTYRS 386
            ::.::..:...:|:..:|.|..|....:..| .:.:....|...::|:|||:.||||:......|
  Rat   238 EQYDMTALFQHLGMIDVFSEIKADLSGMCPEKDLCVSKFVHECVVEVNEEGTEAAAASAADCCYS 302

  Fly   387 ARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            .....|. |..:.||||.|....:.||||.|.:..|
  Rat   303 CSEYTPT-FCADRPFLFFIRHNQTNSILFCGRFSSP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	99/356 (28%)
Serpinb9d	NP_001100821.1	SERPIN	1..337	CDD:294093	99/359 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820