Protein Alignment Spn88Ea and SERPIND1

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_000176.2
• Gene: SERPIND1 / 3053
• HGNCID: 4838
• Length: 499
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 115/416 - (27%)
• Similarity: 185/416 - (44%)
• Gaps: 68/416 - (16%)

  Fly    32 QRLNLYKGQQNFAVSMLNVIR-QSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHL-DW 94
            ||||:...:  ||.::..|:: |....:|:|.:|.....|:.:...|..|:|.:::..:||. |:
Human   124 QRLNILNAK--FAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDF 186

  Fly    95 --ADSKEVVRS-----------------AYILEKMNRKERQSKMP--LEFSSADR-IFFANDLHV 137
              |.||..:.:                 .|.|..:|....|.:.|  |:|.:..| .:||
Human   187 VNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFA----- 246

  Fly   138 TECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKG 202
                      |.|..||......|:  .|:.|.|.|...|::.|  :.|.|.|::::.|..|.||
Human   247 ----------EAQIADFSDPAFISK--TNNHIMKLTKGLIKDAL--ENIDPATQMMILNCIYFKG 297

  Fly   203 QWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSS 267
            .|:::|..|.|....|..:......|||||.||.||...|::|...:|||.|
Human   298 SWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEY------------- 349

  Fly   268 PDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILA 332
               ...||| ||:.|...:.::.:.::|....::...|....|..||.||||:.|:...|...|.
Human   350 ---VGGISM-LIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLK 410

  Fly   333 KMGVSKMFDESVATFDDLTSETISIGDSKHVAKIKVDEEGSTAAAATVL-FTYRSARPVEPAKFE 396
            .||:..:||:: .....::.:.|:|...||...|.|:|||:.|...|.: |...|.:    .:|.
Human   411 LMGIRMLFDKN-GNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQ----VRFT 470

  Fly   397 CNHPFLFVIYDRTSRSILFTGIYRDP 422
            .:.||||:||:..:..:||.|...:|
Human   471 VDRPFLFLIYEHRTSCLLFMGRVANP 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	110/404 (27%)
SERPIND1	NP_000176.2	HCII	62..497	CDD:239002	115/416 (28%)
		Chemotactic activity	68..79
		2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like)	73..97
		Glycosaminoglycan-binding site	192..212		1/19 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020