DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb13

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	404	Identity:	118/404 - (29%)
Similarity:	190/404 - (47%)	Gaps:	72/404 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 TPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDW--------ADSKEVVRSAYILEKMN 111
            |.:.||||||.....|:.:...|:.|.|..||.|||:.:.        ::.||:       ||..
  Rat    22 TSDGNVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSSRLKSEEKEI-------EKTE 79

  Fly   112 RKERQ-SKMPLEFSSADRIFFANDLHVTECARNRLAEE--------------------VQQIDFK 155
            ....| .|:..|.|...:.:   ||.::    |||..|                    ::.:||.
  Rat    80 EIHHQFQKLLTEISKPTKDY---DLIIS----NRLYGERTYLFLQKYIDYVEKYYHASLEPVDFV 137

  Fly   156 SQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYT 220
            :..:||||:||.|:..||:::::::.....:...|:|||.|..|.||.|..:||.|.|....|:.
  Rat   138 NAADESRKKINSWVESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEHTKEEDFWL 202

  Fly   221 SPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNS 285
            :.:....|.||.|..:|...:.|.|:|.::.:||:               |||.||.::||. :.
  Rat   203 NKNISKPVQMMAQCSSFSFTLLEDLQAKIVGIPYK---------------NSDFSMFVLLPN-DI 251

  Fly   286 NSLEDVLSRLNADSLDD-----SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVA 345
            :.||.::.:|:.:.|.:     .|||   |::::.||:.:.|:..:|.|.|..:|:...|.|. |
  Rat   252 DGLEKIIDKLSPEKLVEWTSPGQLKQ---RKVDLRLPRLKVEETYDLQPTLEAVGIHSAFSEH-A 312

  Fly   346 TFDDLTSET-ISIGDSKHVAKIKVDEEGSTAAAAT-VLFTYRSARPVEPAKFECNHPFLFVIYDR 408
            .:..:::.: :...:..|.:.:.|.|||..|.|.| |.|...||...|  ...|||||||.:..|
  Rat   313 DYSGMSAHSGLQTQNFLHRSFLVVTEEGVEATAGTGVGFKVLSAASCE--LVHCNHPFLFFVRHR 375

  Fly   409 TSRSILFTGIYRDP 422
            .|.||||.|.:..|
  Rat   376 ESDSILFFGRFSSP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	117/399 (29%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	117/402 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820