DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb3

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001382662.1	Gene:	Serpinb3 / 304688	RGDID:	1549766	Length:	387	Species:	Rattus norvegicus

Alignment Length:	410	Identity:	111/410 - (27%)
Similarity:	195/410 - (47%)	Gaps:	53/410 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVVR 102
            |....|.:.:...:|.|  .:|:|:||.|...||.:...|:.|:|||::.|.|.|.....|...:
  Rat     6 KATTQFTLELYRQLRDS--EDNIFYSPLSIMTALAMLQLGAKGNTEKQIEKALQLSETTKKPKEK 68

  Fly   103 SAYILEKMNRKER---------QSKMPLEFSSADRIF----------FANDLHVTECARNRLAEE 148
            ||...::.|..|:         :|....:..|.:.|:          |..|:      :......
  Rat    69 SADSHDEENVHEQFRKIMNQLNKSNGAYDLKSPNSIYGAKGFPFLQTFMEDI------KKYYQAN 127

  Fly   149 VQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKT 213
            |:.:||....|||:|:||.|:..:|:.:|:::.....:...|.|||.||.|.||||..:|..::|
  Rat   128 VESLDFAHAAEESQKKINSWVENKTNGKIKDLFPRGSLNSSTILVLVNAVYFKGQWNHKFDEQRT 192

  Fly   214 VPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVL 278
            ....|:.:.:....|.||:|...|.....|.::|.::::||:               ..::||.:
  Rat   193 REDKFWLNKNTSKPVQMMRQTNEFNFIFLEDVQAKMVEIPYK---------------GKELSMFI 242

  Fly   279 ILPPFNSNSLEDVLSRLNADSLDDSLKQAMPR-----EIEVSLPKFEFEQRLELNPILAKMGVSK 338
            :| |...:.|:.:..:|:||:|   |....|:     ::.:|||:|:.:::.:|...|..||:..
  Rat   243 LL-PMEIDGLKKLEEKLSADTL---LAWTSPKNMRMTQLNLSLPRFKVQEKYDLPGPLEHMGMVD 303

  Fly   339 MFDESVATFDDLTS-ETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFL 402
            .|:...|.|..::| :.:.:....|.:.::|:|||:.|||||.:.|...:.| ...:|.||.||:
  Rat   304 AFNPQKADFSGMSSTKGLVVSKVLHKSFLEVNEEGAEAAAATGVETRILSAP-RTTEFTCNRPFI 367

  Fly   403 FVIYDRTSRSILFTGIYRDP 422
            ..|....:.||||.|....|
  Rat   368 VFIKPNNTNSILFFGRVSSP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	109/404 (27%)
Serpinb3	NP_001382662.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920