DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and LOC299277

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	444	Identity:	118/444 - (26%)
Similarity:	196/444 - (44%)	Gaps:	70/444 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILSISLMAVLPAIALA---GLCGVEPDAGL-LDQRLNLYKG-----QQNFAVSMLNVIRQSTPNE 58
            :|.|....:.|| ||.   |..|..|:... .|.:..|..|     ..:||.|:...:....||:
  Rat     6 VLGIITAVICPA-ALCCRDGTLGRHPEVQKDQDTKKQLDSGTLASINTDFAFSLYKELALKNPNK 69

  Fly    59 NVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV-VRSAY--ILEKMNRKERQSKMP 120
            |:.|||.|...||.....|:.|:|.:|:.:.|..:..::.|: :...|  :|:::::...|.
  Rat    70 NIAFSPLSISAALASLSLGAKGNTLQEILEGLKFNLTETTEIDIHQNYRDLLQRLSQPGGQG--- 131

  Fly   121 LEFSSADRIFFANDLHV----TECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNML 181
             :.|.|:.:|....|.:    .|.|:.....||...||: ||.|:||.|||::..|:..:|:.|:
  Rat   132 -QISRANLLFVEKHLQILNGFKEKAKALYQTEVFATDFQ-QTCEARKFINDYVMIQSQGKIKEMV 194

  Fly   182 SADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKG-TFLLNVDEQL 245
            :  |:..||.:|:.|.....|||...|..:.|....|.........|.||:.:. |.....||:|
  Rat   195 T--ELEERTSIVMLNFLLFTGQWSVPFDPDDTFMGKFILDSRRPVKVLMMKTEDLTTPYFWDEEL 257

  Fly   246 RAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSL---DDSLKQA 307
            :..|::|.|:                .....:.|||  :...:|.|.:.|:..:|   .||||
  Rat   258 KCTVVELNYK----------------GHGKAMFILP--DQGKMEQVEASLHPGTLRKWTDSLK-- 302

  Fly   308 MPREI-EVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLT----SETISIGDSKHVAKIK 367
             ||.| |:.||||...:..:|..||.::|:..:|:    |..||:    ::.:.:....|...:.
  Rat   303 -PRIIDELHLPKFSLSKTYKLENILPELGIMDVFN----TQADLSGIAGAKDVRVSQMIHNTVLG 362

  Fly   368 VDEEGSTAAAAT-VLFTYRSARPVEPAKFECN-----HPFLFVIYDRTSRSILF 415
            :.|.|:.|.|.| |.:.:|      |||....     ..||:::.:..|..|.|
  Rat   363 MAETGTEAEATTRVEYNFR------PAKLNDTFVNFVRKFLYMVLEPNSELISF 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	107/404 (26%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	109/412 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100