DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb6e

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_006253937.2	Gene:	Serpinb6e / 291087	RGDID:	1561697	Length:	379	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	115/400 - (28%)
Similarity:	204/400 - (51%)	Gaps:	38/400 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHL------DW 94
            |.:....||:.:|.|:.:.: ::||||||.|.:.:|.:...|::|.|..:::|||.|      ..
  Rat     4 LLEANATFALKVLRVLGEDS-SKNVFFSPLSMFSSLSMILLGANGTTASQISKVLSLYNCNGNGG 67

  Fly    95 ADSKEVVRSAYILEKMNRKERQSKMPLEFSSADRIFFANDLHV----TECARNRLAEEVQQIDFK 155
            .|..:..:|  :|.::|:.:|:..:    .:::.:|..:...:    .:..|.....|::.:|||
  Rat    68 GDFHQCFQS--LLTEVNKSDRRHML----KTSNSVFVEDSFEILASFKDSCRKFYEAEIENMDFK 126

  Fly   156 SQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYT 220
            ...|:||:.||.|:||:|.|.||.:||...:...|:|||.|:.|.||.|...|..|.|..|||..
  Rat   127 GAPEQSRQHINTWVAKKTEDVIRELLSPGTVNSNTQLVLMNSFYFKGNWEKPFNKEDTREMPFKV 191

  Fly   221 SPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNS 285
            |.:...:|.||..|..|.....|.:...:..|||.               .:.:|:.::||. ..
  Rat   192 SKNEKKIVQMMFNKSNFRTYHVEDISTTLALLPYL---------------GNQLSITIMLPD-EY 240

  Fly   286 NSLEDVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFD 348
            ..|..|.:::..:.|.:  .|:.....|:|:.||:|:.|:..::..:|.|:|::..|::..|.|.
  Rat   241 VELRTVENQITYEKLIEWTRLENMQEEEVEILLPRFKLEESYDMKNVLCKLGMTNAFEDGRADFS 305

  Fly   349 DLTSET-ISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVIYDRTSRS 412
            .::|:. :.:....|.:.::|:|||:.|||.|.:.|..|  |:.|.....:|||||:|.|..:::
  Rat   306 GISSKPGLFLSKVVHKSVVEVNEEGTEAAAPTEIVTMGS--PLSPQCLVADHPFLFLIQDDRNKA 368

  Fly   413 ILFTGIYRDP 422
            |||.|.:..|
  Rat   369 ILFLGRFSSP 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	113/392 (29%)
Serpinb6e	XP_006253937.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010