Protein Alignment Spn88Ea and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 397
• Identity: 111/397 - (27%)
• Similarity: 192/397 - (48%)
• Gaps: 52/397 - (13%)

  Fly    43 FAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWAD---------SK 98
            |.:.:.:.:::|:|..|:||||:|...:|.:.:.|:.|.|..:|:|.||.|..:         :.
Mouse    11 FTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHFDSVEDIHSCFQSLTA 75

  Fly    99 EVVR--SAYILEKMNR---KERQSKMPLEFSSADRIFFANDLHVTECARNRLAEEVQQIDFKSQT 158
            ||.:  :::.|:..||   ::..:.:| ||.::.:..::.||              ..:||:..:
Mouse    76 EVSKLGASHTLKLANRLYGEKTYNFLP-EFLASTQKMYSADL--------------AAVDFQHAS 125

  Fly   159 EESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPS 223
            |::||:||.|:..||..:|..:|:...:...|:|||.||.|.||.|..||.|.:|:..||..:..
Mouse   126 EDARKEINQWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKK 190

  Fly   224 NYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILP---PFNS 285
            :...|.||.||..|.......|:..||::||               :..::|||::||   ...|
Mouse   191 DTKTVKMMYQKKKFPFGYISDLKCKVLEMPY---------------QGGELSMVILLPEDIEDES 240

  Fly   286 NSLEDVLSRLNADSLDDSLKQAMPREIE--VSLPKFEFEQRLELNPILAKMGVSKMFDESVATFD 348
            ..|:.:..:|....|.:..|....|.|:  |.||:|:.|:...||..|..:||..:|....|...
Mouse   241 TGLKKIEEQLTLGKLHEWTKHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLS 305

  Fly   349 DLT-SETISIGDSKHVAKIKVDEEGSTAAAAT--VLFTYRSARPVEPAKFECNHPFLFVIYDRTS 410
            .:: |..:.:....|.:.:.|:|:|:.|||||  ::.......|.....|..:|||||.|....:
Mouse   306 GMSGSRDLFVSKIVHKSFVDVNEQGTEAAAATGGIIQVLCEKMPTPQEVFTVDHPFLFFIRHNPT 370

  Fly   411 RSILFTG 417
            .:::|.|
Mouse   371 ANMIFFG 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	serpin_crustaceans_chelicerates_insects	36..422	CDD:381059	111/397 (28%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	111/397 (28%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		9/26 (35%)