Protein Alignment Spn88Ea and Serpina3b

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_766612.1
• Gene: Serpina3b / 271047
• MGIID: 2182835
• Length: 420
• Species: Mus musculus
• Alignment Length: 439
• Identity: 102/439 - (23%)
• Similarity: 199/439 - (45%)
• Gaps: 76/439 - (17%)

  Fly     4 LSISLMAVLPAIALAGLCGVEPDAGLLDQRLNLYKGQQ---------------NFAVSMLNVIRQ 53
            |.:.:..:.||:    :|..:   |.|.....:.|||.               :||.|....:..
Mouse     7 LGLLMAEICPAV----ICCSD---GTLGMHNAVQKGQDTQKQLDSLTLASINTDFAFSFYKELAL 64

  Fly    54 STPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV-VRSAY--ILEKMNRKER 115
            ..|::|:.|||:....||.....|:.|:|.:|:.:||..:..::.|. :...:  :|::::....
Mouse    65 KNPHKNIAFSPFGIATALNSLTLGAKGNTLEEILEVLKFNLTETSEADIHQGFKHLLQRLSHPGD 129

  Fly   116 QSKMPLEFSSADRIFFANDLHV----TECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQ 176
            |    ::..:.:.:|....|.:    .|.||.....||...:|: |..|:.|.||.:::.||..:
Mouse   130 Q----VQIRTGNALFVEKHLQILAEFKEKARALYHTEVFTANFQ-QPHEAMKLINSYMSNQTQGK 189

  Fly   177 IRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNV 241
            |:.::|  ::...|.:|:.|..:.|.:|:..|.::.|....|....|.:..|.||:.|     |:
Mouse   190 IKELVS--DMDGNTSMVIVNDLFFKAEWMVPFNSDDTFMGKFIVDRSRHVKVPMMKTK-----NL 247

  Fly   242 ------DEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSL 300
                  ||:|:..|::|.|:                .:...:.|||  :...::.|.:.|...:|
Mouse   248 RTPYFRDEELKCTVVELNYK----------------GNGKAMFILP--DQGKMQQVEASLQPGTL 294

  Fly   301 DDSLKQAMPREI-EVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSET----ISIGDS 360
            ....|...||:| |:.||||...|...|..||.::|:.::|    :|..||:..|    |::.:.
Mouse   295 KKWRKSLRPRKIKELHLPKFSLSQHYNLEDILPELGIRELF----STQADLSGITGVKNITVSEM 355

  Fly   361 KHVAKIKVDEEGSTAAAATVL-FTYRSARPVEPAKFECNHPFLFVIYDR 408
            .|..::.:.|:|:...|.|:: :.:.||: ::|...:....||:::.|:
Mouse   356 IHSTELDMTEKGTEGDAITIVGYNFMSAK-LKPVFVKFEDQFLYIVLDQ 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	95/404 (24%)
Serpina3b	NP_766612.1	SERPIN	51..414	CDD:294093	93/388 (24%)
		RCL	367..392		6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010