Protein Alignment Spn88Ea and SERPINA11

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 95/392 - (24%)
• Similarity: 171/392 - (43%)
• Gaps: 39/392 - (9%)

  Fly    42 NFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVVRSAYI 106
            |||:.:...:....|. |:||||.|....|.|...|:..:|...:.:.|..:..::.|    |.|
Human    56 NFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPE----ADI 115

  Fly   107 LEKMNRKERQSKMP---LEFSSADRIFFANDLHVTECARNRLAEEVQQIDFKSQTEES---RKQI 165
            .:..........:|   ||....:.:|....|...:...:.:.|......|.:...:|   .:||
Human   116 HQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI 180

  Fly   166 NDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQW---LSQFKTEKTVPMPFYTSPSNYSL 227
            ||::.:||:.|:.:.|  .|.:..|.:||||..:.|.:|   .|:::|:|  ...|:........
Human   181 NDYLRRQTYGQVVDCL--PEFSQDTFMVLANYIFFKAKWKHPFSRYQTQK--QESFFVDERTSLQ 241

  Fly   228 VSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVL 292
            |.||.||.......|:.|...|||:.||                .:...:|:||  :...::.|.
Human   242 VPMMHQKEMHRFLYDQDLACTVLQIEYR----------------GNALALLVLP--DPGKMKQVE 288

  Fly   293 SRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSE-TIS 356
            :.|...:|....:..:|..:::.||:|.......|..||.::|::.:.:.. |.|..:|.: ..:
Human   289 AALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLE-ADFSGVTGQLNKT 352

  Fly   357 IGDSKHVAKIKVDEEGSTAAAATVLFTY-RSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYR 420
            |....|.|.:.:.|:|:.|.||:.|.:. .|...:.......|.|||.::::.|::|:||.|...
Human   353 ISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVV 417

  Fly   421 DP 422
            :|
Human   418 NP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	94/387 (24%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	94/387 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010