Protein Alignment Spn88Ea and Serpina1

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_071964.2
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 107/430 - (24%)
• Similarity: 191/430 - (44%)
• Gaps: 52/430 - (12%)

  Fly    15 IALAGLCGVEP----------DAGLLDQRLNLYKGQQN---FAVSMLNVIRQSTPNENVFFSPYS 66
            :.|||||.:.|          |....||.....|...|   ||.|:...:...:...|:||||.|
  Rat    10 LLLAGLCCLAPSFLAEDAQETDTSQQDQSPTYRKISSNLADFAFSLYRELVHQSNTSNIFFSPMS 74

  Fly    67 TYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV-VRSAY--ILEKMNRKERQSKMPLEFSSADR 128
            ...|..:...||.|||.|::.:.|..:.....|. :..|:  :|:.:||.:.:    |:.::.:.
  Rat    75 ITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPEADIHKAFHHLLQTLNRPDSE----LQLNTGNG 135

  Fly   129 IFFANDLHVTEC----ARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPR 189
            :|...:|.:.|.    .:|....|...::| :.:||::|.|||::.|.|..:|.:::.  ::...
  Rat   136 LFVNKNLKLVEKFLEEVKNNYHSEAFSVNF-ADSEEAKKVINDYVEKGTQGKIVDLMK--QLDED 197

  Fly   190 TRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPY 254
            |...|.|..:.||:|...|..|.|....|:...|....|.||.:.|.|.::....|.:.||.:.|
  Rat   198 TVFALVNYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRLGMFDMHYCSTLSSWVLMMDY 262

  Fly   255 RTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKF 319
            .                .:.:.:.:||  :...::.:...|..|.:...|.....|...:..||.
  Rat   263 L----------------GNATAIFLLP--DDGKMQHLEQTLTKDLISRFLLNRQTRSAILYFPKL 309

  Fly   320 EFEQRLELNPILAKMGVSKMFDESVATFDDLTSET-ISIGDSKHVAKIKVDEEGSTAAAATVLFT 383
            .......|..:|:.:|::::|:.. |....:|.:. :.:..:.|.|.:.:||.|:.||.|||:
  Rat   310 SISGTYNLKTLLSSLGITRVFNND-ADLSGITEDAPLKLSQAVHKAVLTLDERGTEAAGATVV-- 371

  Fly   384 YRSARPVE-PAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
              .|.|:. |.:.:.:|||:|:|.:..::|.||.|...||
  Rat   372 --EAVPMSLPPQVKFDHPFIFMIVESETQSPLFVGKVIDP 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	95/391 (24%)
Serpina1	NP_071964.2	alpha-1-antitrypsin_like	49..406	CDD:239011	94/386 (24%)
		RCL	367..386		6/22 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010