DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpine1

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_036752.2	Gene:	Serpine1 / 24617	RGDID:	3249	Length:	402	Species:	Rattus norvegicus

Alignment Length:	402	Identity:	112/402 - (27%)
Similarity:	184/402 - (45%)	Gaps:	45/402 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 YKGQQ--NFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKE 99
            :..||  ||.|.:...:.|::.:.||.||||.....|.:....::|.|.:::...:..:.::.
  Rat    30 HTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISER-- 92

  Fly   100 VVRSAYILEKMNRKERQSKMPLEFSSADRIFFANDL--------HVTECARNRLAEEVQQIDFKS 156
              .:|..|.|::::...|....|.|:||.||...||        |..:..|.    .|:|:|| |
  Rat    93 --GTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRT----TVKQVDF-S 150

  Fly   157 QTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTS 221
            :.|.:|..||||:.:.|...|.::|:...:...|||||.||.|..|||.:.|....|....|:.|
  Rat   151 EMERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKS 215

  Fly   222 PSNYSLVSMMQQKGTFLLNVDEQLRAH---VLQLPYRTVFESQEKEDSSPDENSDISMVLILPPF 283
            ..:...|.||.|...|..........|   :|:|||               ....:||.:..|..
  Rat   216 DGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPY---------------HGETLSMFIAAPFE 265

  Fly   284 NSNSLEDVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVAT 346
            ....|..:.:.|:|:.:..  |....:||.:  .||||..|..::|...|.|:|::.:|..:.|.
  Rat   266 KDVPLSAITNILDAELIRQWKSNMTRLPRLL--ILPKFSLETEVDLRGPLEKLGMTDIFSSTQAD 328

  Fly   347 FDDLT-SETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVIYDRTS 410
            |..|: .|.:|:..:....||:|:|.|:.|:::|.:..  ||| :.|.:...:..||||:....:
  Rat   329 FTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILV--SAR-MAPTEMVLDRSFLFVVRHNPT 390

  Fly   411 RSILFTGIYRDP 422
            .:|||.|...:|
  Rat   391 ETILFMGQLMEP 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	111/395 (28%)
Serpine1	NP_036752.2	serpin	29..402	CDD:422956	111/400 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020