DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb6d

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001070258.1	Gene:	Serpinb6d / 238568	MGIID:	2667783	Length:	375	Species:	Mus musculus

Alignment Length:	403	Identity:	113/403 - (28%)
Similarity:	193/403 - (47%)	Gaps:	47/403 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLD--WADSK 98
            |.|....||..:|..:...| ::|:|.||.|...:|.:...|:..:|.:::.:.|.||  .:|..
Mouse     4 LPKLNTKFAFKLLKALDDDT-SKNIFLSPPSIASSLAMTLLGAKENTARQIRQTLSLDKCSSDPC 67

  Fly    99 EVVRSAY--ILEKMNRKERQSKMPLEFSSADRIFFANDLHV----TECARNRLAEEVQQIDFKSQ 157
            |.:...:  :|.::|:.:....:..|    :|:|.....|:    .:.::.....|::::|||..
Mouse    68 EDIHQDFHLLLNEVNKTDPGIILKTE----NRLFVEKTFHIKKSFKDASQKFYKAEIEELDFKGD 128

  Fly   158 TEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSP 222
            ||:||:.||.|:.|.|.::|:::||...:...|||||.|..|.||.|...|..|.|..|||..|.
Mouse   129 TEQSRQHINTWVTKNTDEKIKDLLSPGSVNSNTRLVLVNDFYFKGYWEKPFNKEDTREMPFRVSK 193

  Fly   223 SNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNS 287
            :....|.||.||.||.:...|::...:|.|||               ..:.::|:::||.
Mouse   194 NVVKPVQMMFQKSTFKITYIEEISTKILLLPY---------------AGNKLNMIIMLPD----- 238

  Fly   288 LEDVLSRLNADSLD-------DSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVA 345
             |.|..|:....:.       .||.:....|:||.||:|:.|:..::|.:|.|||::..|:|..|
Mouse   239 -EHVELRMLEKKMTYEKFVEWTSLDKMNEEEVEVFLPRFKLEEIYDMNNVLYKMGMTDAFEEGRA 302

  Fly   346 TFDDLTS-ETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVIYDRT 409
            .|..::| :.:.:....:.|.|:|.|:|:..||||.: ....|.|.... |..:|||:|.   ..
Mouse   303 DFSGISSKQGLFLSKVIYKAFIEVIEKGTKVAAATDI-VMMGASPTTHT-FCADHPFIFT---HM 362

  Fly   410 SRSILFTGIYRDP 422
            :...:..|.:..|
Mouse   363 TEDFMIIGRFSSP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	110/395 (28%)
Serpinb6d	NP_001070258.1	SERPIN	4..375	CDD:294093	112/401 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820