Protein Alignment Spn88Ea and Serpina10

DIOPT Version :10

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_659083.2
• Gene: Serpina10 / 217847
• MGIID: 2667725
• Length: 448
• Species: Mus musculus
• Alignment Length: 418
• Identity: 113/418 - (27%)
• Similarity: 195/418 - (46%)
• Gaps: 60/418 - (14%)

  Fly    31 DQRLNLYKGQQ------NFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKV 89
            |:...|...||      :|..::|..| ....:.||.|||:....|::....|:.|:|:.::...
Mouse    68 DEEYWLRASQQLSNETSSFGFNLLRKI-SMRHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIENG 131

  Fly    90 LHLDWADSKEVVRSA--YILEKMNRKERQ---SKMPLEFSSADRIFFANDLHVTECARNRLAEEV 149
            |:|      :.:..|  .||..:.:|.::   |...|..|.....|...|..:.|...| |:::.
Mouse   132 LNL------QALSQAGPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFDIKETYFN-LSKKY 189

  Fly   150 QQIDFKS----QTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKT 210
            ..|::.|    .:.::|..||..|.|:|..:|..:.  |||.|.|:|:|.:....||:||:.|..
Mouse   190 FDIEYVSINFQNSSQARGLINHCIVKETEGKIPKLF--DEINPETKLILVDYVLFKGKWLTPFDP 252

  Fly   211 EKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDIS 275
            ..|....|:........|.||.::|.|....|::.|.|:|:|||:              .|:.:.
Mouse   253 SFTEADTFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQ--------------GNATML 303

  Fly   276 MVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMF 340
            :||:....:..:|||.|:   .|.::..|:....|::||..|||:..||.|::.:|.:||:.::|
Mouse   304 VVLMEKTGDYLALEDYLT---VDLVETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLF 365

  Fly   341 DESVATFDDLTSETISIGDSKHVAKI------KVDEEGSTAAAATV--LFTYRSARPVEPAKFEC 397
            ..|.    || ||..::..:..|:::      :|||.|:.|.:.|:  :..|..     |...:.
Mouse   366 STSA----DL-SELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSM-----PPAIKV 420

  Fly   398 NHPFLFVIYDRTSRSILFTGIYRDPKTI 425
            |.||.|:||:..||.:||.|...:|..:
Mouse   421 NRPFHFIIYEEMSRMLLFLGRVVNPTVL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	serpin_crustaceans_chelicerates_insects	36..422	CDD:381059	111/408 (27%)
Serpina10	NP_659083.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..70		1/1 (100%)
		serpinA10_PZI	71..446	CDD:381011	111/411 (27%)
		Heparin-binding. /evidence=ECO:0000250	140..157		4/16 (25%)