Protein Alignment Spn88Ea and Serpina3n

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_033278.2
• Gene: Serpina3n / 20716
• MGIID: 105045
• Length: 418
• Species: Mus musculus
• Alignment Length: 452
• Identity: 126/452 - (27%)
• Similarity: 202/452 - (44%)
• Gaps: 71/452 - (15%)

  Fly     9 MAVLPAIAL--AGLCGVE---PDAGL---------------LDQRLNLYKGQQNFAVSMLNVIRQ 53
            ||.:.|:.|  ||:|...   ||..|               ||. |.|.....:||.|:...:..
Mouse     1 MAFIAALGLLMAGICPAVLCFPDGTLGMDAAVQEDHDNGTQLDS-LTLASINTDFAFSLYKELVL 64

  Fly    54 STPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEV-VRSAY--ILEKMNRKER 115
            ..|::|:.|||.|...||.:...|:.|:|.:|:.:.|..:..::.|. :...:  :|:::|
Mouse    65 KNPDKNIVFSPLSISAALAVMSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLN---- 125

  Fly   116 QSKMPLEFSSADRIFFANDLHV----TECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQ 176
            |.|..::.|:...:|......:    .|.||.....|....||: |..:::|.|||::.|||...
Mouse   126 QPKDQVQISTGSALFIEKRQQILTEFQEKARALYQAEAFTADFQ-QPRQAKKLINDYVRKQTQGM 189

  Fly   177 IRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKG-TFLLN 240
            |:.::|  ::..||.:||.|..|.|.:|...|....|....||.......:|.||..:. |....
Mouse   190 IKELVS--DLDKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFYAGKRRPVIVPMMSMEDLTTPYF 252

  Fly   241 VDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSL---DD 302
            .||:|...|::|.|                ..:.|.:.|||  :...::.|.:.|..::|   .:
Mouse   253 RDEELFCTVVELKY----------------TGNASAMFILP--DQGKMQQVEASLQPETLRKWKN 299

  Fly   303 SLKQAMPREI-EVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSET----ISIGDSKH 362
            |||   ||.| |:.||||.......|..:|:|:|:.::|    :|..||::.|    :.:....|
Mouse   300 SLK---PRMIDELHLPKFSISTDYSLEDVLSKLGIREVF----STQADLSAITGTKDLRVSQVVH 357

  Fly   363 VAKIKVDEEGSTAAAAT-VLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDPK 423
            .|.:.|.|.|:.||||| |.|...||: :.|.....|.|||.:|:|..:....|.....:||
Mouse   358 KAVLDVAETGTEAAAATGVKFVPMSAK-LYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	110/396 (28%)
Serpina3n	NP_033278.2	serpinA3_A1AC	37..418	CDD:381019	114/414 (28%)
		RCL	367..392		11/25 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010