DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Ea and Serpina1d

DIOPT Version :9

Sequence 1:NP_524954.2 Gene:Spn88Ea / 49804 FlyBaseID:FBgn0028984 Length:427 Species:Drosophila melanogaster
Sequence 2:NP_033272.1 Gene:Serpina1d / 20703 MGIID:891968 Length:413 Species:Mus musculus


Alignment Length:442 Identity:118/442 - (26%)
Similarity:204/442 - (46%) Gaps:59/442 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 SISLMAVLPAIALAGLCGVEP----------DAGLLDQRLNLYKGQQN---FAVSMLNVIRQSTP 56
            |||...:|    |||||.:.|          |....||....::...|   ||:.:...:...:.
Mouse     4 SISWSLLL----LAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFALRLYRELVHQSN 64

  Fly    57 NENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKE--VVRS-AYILEKMNRKERQSK 118
            ..|:||||.|...|..:...||.|||..::.:.|..:...:.|  :.:| .::|:.:||.:.:  
Mouse    65 TSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSE-- 127

  Fly   119 MPLEFSSADRIFFANDLHVTEC----ARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRN 179
              |:.|:.:.:|..|||.:.|.    |:|....||..::| :::||::|.|||::.|.|..:|  
Mouse   128 --LQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF-AESEEAKKVINDFVEKGTQGKI-- 187

  Fly   180 MLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQ 244
            :.:..::...|...|||....||:|...|..|.|....|:...|....|.||...|...::....
Mouse   188 VEAVKKLDQDTVFALANYILFKGKWKQPFDPENTEEAEFHVDESTTVKVPMMTLSGMLDVHHCSM 252

  Fly   245 LRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMP 309
            |.:.||.:.|.                .:.:.|.:||  :...::.:...||.:.:...|.....
Mouse   253 LSSWVLLMDYA----------------GNTTAVFLLP--DDGKMQHLEQTLNKELISQFLLNRRR 299

  Fly   310 REIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTSETISIGDSK--HVAKIKVDEEG 372
            .:.::.:|:........|..:::.:|::::|:.. |....:|.|...:..||  |.|.:.:||.|
Mouse   300 SDAQIHIPRLSISGNYNLKTLMSPLGITRIFNNG-ADLSGITEENAPLKLSKAVHKAVLTIDETG 363

  Fly   373 STAAAATVL--FTYRSARPVEPAKFECNHPFLFVIYDRTSRSILFTGIYRDP 422
            :.|||||||  .|| |..|:  .:|:  |||||:|::..::|.:|.|...||
Mouse   364 TEAAAATVLQVATY-SMPPI--VRFD--HPFLFIIFEEHTQSPIFVGKVVDP 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EaNP_524954.2 SERPIN 39..419 CDD:238101 103/393 (26%)
Serpina1dNP_033272.1 SERPIN 53..410 CDD:214513 100/387 (26%)
RCL 368..387 10/23 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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