DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Ea and Serpinb3a

DIOPT Version :9

Sequence 1:NP_524954.2 Gene:Spn88Ea / 49804 FlyBaseID:FBgn0028984 Length:427 Species:Drosophila melanogaster
Sequence 2:NP_033152.3 Gene:Serpinb3a / 20248 MGIID:3573933 Length:387 Species:Mus musculus


Alignment Length:397 Identity:115/397 - (28%)
Similarity:200/397 - (50%) Gaps:37/397 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 FAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWADSKEVVRSAYIL 107
            |.:.:...:|:|  :.|:|:||.|...||.:...|:.|:|||::.|||..:....|...:||:..
Mouse    11 FTLELYRQLRES--DNNIFYSPISMMTALAMLQLGAKGNTEKQIEKVLQFNETTKKTTEKSAHCH 73

  Fly   108 EKMNRKERQSKMPLEFSSADRIF---FANDLH----------VTECARNRLAEEVQQIDFKSQTE 159
            ::.|..|:..|:..:.:.::..:   .||.::          ..|..:......|:.:||:...|
Mouse    74 DEENVHEQFQKLMTQLNKSNDAYDLKAANSIYGAKGFPFVQTFLEDIKEYYQANVESLDFEHAAE 138

  Fly   160 ESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSN 224
            ||.|:||.|:..||:.:|:::.....:...|.:||.||.|.||||..:|..:.|....|:.:.:.
Mouse   139 ESEKKINSWVESQTNGKIKDLFPNGSLNRSTIMVLVNAVYFKGQWNHKFDEKHTTEEKFWLNKNT 203

  Fly   225 YSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNSNSLE 289
            ...|.||:|...|.....|.::|.::::||:               ..::||:::| |...|.|:
Mouse   204 SKPVQMMKQNIEFNFMFLEDVQAKIVEIPYK---------------GKELSMIVLL-PVEINGLK 252

  Fly   290 DVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFDDLTS 352
            .:..:|.||.|.:  ..:.....|:.:|||:|:.:::.:|...|..||:...||...|.|..::|
Mouse   253 QLEEQLTADKLLEWTRAENMHMTELYLSLPRFKVDEKYDLPIPLEHMGMVDAFDPQKADFSGMSS 317

  Fly   353 -ETISIGDSKHVAKIKVDEEGSTAAAAT-VLFTYRSARPVEPAKFECNHPFLFVIYDRTSRSILF 415
             :.:.:....|.:.::|:|||:.||||| |..:..||:..|  .|.|:|||||.|..|.:.||||
Mouse   318 TQGLVVSKVLHKSFVEVNEEGTEAAAATGVEVSLTSAQIAE--DFCCDHPFLFFIIHRKTNSILF 380

  Fly   416 TGIYRDP 422
            .|....|
Mouse   381 FGRISSP 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EaNP_524954.2 SERPIN 39..419 CDD:238101 114/392 (29%)
Serpinb3aNP_033152.3 SERPIN 5..387 CDD:294093 114/395 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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