DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Ea and Serpina16

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_112098.3	Gene:	Serpina16 / 194604	MGIID:	2684892	Length:	440	Species:	Mus musculus

Alignment Length:	409	Identity:	100/409 - (24%)
Similarity:	165/409 - (40%)	Gaps:	70/409 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHLDWA---DSKEVVR 102
            |.||:|:...:.:|...:||.|||.|....|:|..|....:..:::.:.|.....   |:|..|:
Mouse    70 QKFALSLYTQLPKSKLGKNVIFSPLSITMPLVLLAFQDKPEARRQVLQGLGFGVTGALDAKAAVQ 134

  Fly   103 SAYILEKMNRKERQSKMPLEFSS--ADRIFFAN-----DLHVTECARNRLAEEVQQIDFKSQTEE 160
            ...:|..:        :|.|...  ...:||.:     .......|.:..:.:|..|.|.:. :.
Mouse   135 YGKLLSAL--------LPAEHCGIHTGSLFFIDKTLKPQTTFLTLANSSYSSDVILISFGNH-KL 190

  Fly   161 SRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYTSPSNY 225
            ::|||:..|..:|..::..:|.  .:.|.|.|.|.|....||:|..:|.       |.||...|:
Mouse   191 AKKQIDLAIKVKTQGKVTRLLR--NLKPPTHLFLTNYNLFKGKWKYRFN-------PKYTGMRNF 246

  Fly   226 S-------LVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPF 283
            |       ||.|||:.|.|.|.....:.::|||||:                ..:||.|..||
Mouse   247 SLSNGTNILVPMMQKIGWFQLKYFSHIHSYVLQLPF----------------TCNISGVFFLP-- 293

  Fly   284 NSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFD 348
            |...|::....|...|.:..::....|:..:..|||.....|:|..........|:|::.:
Mouse   294 NDGDLKECEKALLEQSFNTWIQPFPLRKRWLFFPKFSIPVALQLESFKHVNSSLKLFNKRM---- 354

  Fly   349 DLTSETIS-----IGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEP--AKFECNHPFLFVIY 406
            ||:..|:.     :..:.|.|::.|.|:|.....:      .|....||  |....|..||.:|.
Mouse   355 DLSGITLQKAPLRVTMAVHRAELAVSEDGEGEDVS------NSRVNPEPGLAALHFNRSFLLLIL 413

  Fly   407 DRTSRSILFTGIYRDPKTI 425
            |..|:|:||.|...:|..:
Mouse   414 DEASKSLLFMGRVLNPTRV 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	99/401 (25%)
Serpina16	XP_112098.3	serpin	61..431	CDD:393296	100/406 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100