Protein Alignment Spn88Ea and Serpind1

DIOPT Version :9

• Sequence 1: NP_524954.2
• Gene: Spn88Ea / 49804
• FlyBaseID: FBgn0028984
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001317976.1
• Gene: Serpind1 / 15160
• MGIID: 96051
• Length: 478
• Species: Mus musculus
• Alignment Length: 415
• Identity: 116/415 - (27%)
• Similarity: 195/415 - (46%)
• Gaps: 66/415 - (15%)

  Fly    32 QRLNLYKGQQNFAVSMLNVIR-QSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHL-DW 94
            ||||:...:  ||.::..|:: |:|.::|:|.:|.....|:.:...|..|:|.:|:..|||. |:
Mouse   103 QRLNILNAK--FAFNLYRVLKDQATTSDNLFIAPVGISTAMGMISLGLRGETHEEVHSVLHFRDF 165

  Fly    95 --ADSKEVVRS-----------------AYILEKMNRKERQSKMPL--EFSSADRIFFANDLHVT 138
              |.||..|.:                 .|.|..:|....|.:.|:  :|.:|.|.|:
Mouse   166 VNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIREDFKAAMREFY------- 223

  Fly   139 ECARNRLAEEVQQIDFKSQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQ 203
                   ..|.|:.:|......|:  .|:.|.|.|...|:..|  :.|.|.|::::.|..|.||.
Mouse   224 -------FAEAQEANFPDPAFISK--ANNHILKLTKGLIKEAL--ENIDPATQMLILNCIYFKGT 277

  Fly   204 WLSQFKTEKTVPMPFYTSPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSP 268
            |:::|..|.|....|..:......|||||.||.||...|::|...:|||.|
Mouse   278 WVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEY-------------- 328

  Fly   269 DENSDISMVLILPPFNSNSLEDVLSRLNADSLDDSLKQAMPREIEVSLPKFEFEQRLELNPILAK 333
              ...|||::::|. ..:.::.:.::|....::...|....|..||.||||:.|:...|..:|..
Mouse   329 --VGGISMLIVVPR-KLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKS 390

  Fly   334 MGVSKMFDESVATFDDLTSETISIGDSKHVAKIKVDEEGSTAAAATVL-FTYRSARPVEPAKFEC 397
            ||::|:|::: .....::.:.|:|...||.:.|.|:|||:.|||.|.: |...|.:    .:|..
Mouse   391 MGITKLFNKN-GNMSGISDQRIAIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQ----VRFTV 450

  Fly   398 NHPFLFVIYDRTSRSILFTGIYRDP 422
            :.||||::|:..:..:||.|...:|
Mouse   451 DRPFLFLVYEHRTSCLLFMGKVTNP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	111/403 (28%)
Serpind1	NP_001317976.1	HCII	43..476	CDD:239002	116/415 (28%)
		2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like)	54..78
		Glycosaminoglycan-binding site. /evidence=ECO:0000250	171..191		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020