DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Ea and Serpinb7

DIOPT Version :9

Sequence 1:	NP_524954.2	Gene:	Spn88Ea / 49804	FlyBaseID:	FBgn0028984	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_569088.1	Gene:	Serpinb7 / 117092	RGDID:	71063	Length:	380	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	115/395 - (29%)
Similarity:	184/395 - (46%)	Gaps:	34/395 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NLYKGQQNFAVSMLNVIRQSTPNENVFFSPYSTYHALLLAYFGSSGDTEKELAKVLHL-----DW 94
            :|......|...:...:..|..|.|||||..|.:.||.|...|:.||..:::.|.||.     ..
  Rat     3 SLAAANAEFGFDLFREMDSSQGNGNVFFSSLSIFTALSLIRLGARGDCARQIDKALHFISPSRQG 67

  Fly    95 ADSKEVVRSAYILEKMNRKERQSKMPLEFSSADRIFFAN--DLHVT--ECARNRLAEEVQQIDFK 155
            ..|...:...|.|:::......|....|.|.|:.:|...  |.|.:  |||.|....:|:::||.
  Rat    68 NSSNSQLGLQYQLKRVLADINSSHKDYELSIANGVFAEKVFDFHKSYMECAENLYNAKVERVDFT 132

  Fly   156 SQTEESRKQINDWIAKQTHDQIRNMLSADEITPRTRLVLANAAYLKGQWLSQFKTEKTVPMPFYT 220
            :..:|:|.:||.||..:||.:|:.:|....::....:||.||.|.||:|.|.|....|:...|.:
  Rat   133 NDIQETRFKINKWIENETHGKIKKVLGDSSLSSSAVMVLVNAVYFKGKWKSAFTKSDTLSCHFRS 197

  Fly   221 SPSNYSLVSMMQQKGTFLLNVDEQLRAHVLQLPYRTVFESQEKEDSSPDENSDISMVLILPPFNS 285
            .......|:||.|:..|.|:..::....:|:|.|                :..|||.::||   .
  Rat   198 PSGPGKAVNMMHQERRFNLSTIQEPPMQILELQY----------------HGGISMYIMLP---E 243

  Fly   286 NSLEDVLSRLNADSLDD--SLKQAMPREIEVSLPKFEFEQRLELNPILAKMGVSKMFDESVATFD 348
            :.|.::.|:|:..:|.|  :.::...:.:.|.||:|:.|:..|:...|..:|:..:|.||.|...
  Rat   244 DDLSEIESKLSFQNLMDWTNSRKMKSQYVNVFLPQFKIEKDYEMRSHLKSVGLEDIFVESRADLS 308

  Fly   349 DLTS-ETISIGDSKHVAKIKVDEEGSTAAAATVLFTYRSARPVEPAKFECNHPFLFVIYDRTSRS 412
            .:.| ..:.:....|.:.|:|.|||:.|.|||.........| |...|..:.||||||  |.:..
  Rat   309 GIASGGRLYVSKLMHKSLIEVSEEGTEATAATESNIVEKLLP-ESTVFRADRPFLFVI--RKNGI 370

  Fly   413 ILFTG 417
            |||||
  Rat   371 ILFTG 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Ea	NP_524954.2	SERPIN	39..419	CDD:238101	114/391 (29%)
Serpinb7	NP_569088.1	SERPIN	4..380	CDD:294093	115/394 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920