Protein Alignment Spn55B and SERPINB7

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_003775.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 111/377 - (29%)
• Similarity: 193/377 - (51%)
• Gaps: 23/377 - (6%)

  Fly     9 ARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--------- 64
            |...|.|...||:.:.......||.||..|:...:||...|:|.::..:|.|.||.
Human     5 AAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNS 69

  Fly    65 ---VSNFPPEVAQTFQFVLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFA- 125
               .|....::.:.|..:...:::.: |.:.|.|:.::.......|....::.|.::.|.::|.
Human    70 SNSQSGLQSQLKRVFSDINASHKDYD-LSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTN 133

  Fly   126 -LNDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWV 189
             |.| ..:.||.||..:|.|||..::.....|.:..:||:||::|||.|...|::..|....|..
Human   134 HLED-TRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKS 197

  Fly   190 GEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLV 254
            .:.....:..|:|:.|||....||.....||:.| :..::|:||||:  ..:..:..||...||:
Human   198 PKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLLPE--NDLSEIENKLTFQNLM 259

  Fly   255 DLAD--KLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPEGVFVSKVLH 316
            :..:  ::|.:.|.|.||:||::.:.|:.:.|:.||:..:|.: :|:.|. :.|...:::|:::|
Human   260 EWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSG-IASGGRLYISRMMH 323

  Fly   317 KATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKNILFAG 368
            |:.|||.||||||.||||..::.:.:.....|:||.|||:||.....|||:|
Human   324 KSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSG 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	108/369 (29%)
SERPINB7	NP_003775.1	serpinB7_megsin	1..380	CDD:381032	111/377 (29%)