DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and SERPIN1

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001320925.1	Gene:	SERPIN1 / 841182	AraportID:	AT1G47710	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	121/367 - (32%)
Similarity:	184/367 - (50%)	Gaps:	35/367 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NVVFSPFSIQTCIALAFAGSQGETADEIAKALHF-----VSNFPPEVAQTFQFVLE--KYRNSNL 88
            ||:|||.||...:::..|||.|.|.|:|...|.|     :::|..|:...   ||.  .......
plant    57 NVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTDQLNSFSSEIVSA---VLADGSANGGPK 118

  Fly    89 LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQA-INAWVNAKTQGKITELVSA 152
            |.|||..::.:....||:::..:::.|.:.:...:|........| :|:|...:|.|.|||::..
plant   119 LSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEVNSWAEKETNGLITEVLPE 183

  Fly   153 DSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCT 217
            .|....|:|:..|||:|||:|..||.|..|:|..|.:.:..:|...:|..|.|.....::  |..
plant   184 GSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNKVTAPFMTSKKKQYVSAYD--GFK 246

  Fly   218 ALEMPY---QDS-DLSMFVLLPQERTGIYALAEKL-KTVNLVDLADKLTVEEVHV---KFPKFKV 274
            .|.:||   ||. ..||:..||....|:..|.:|: .|...:|  :.:...:|.|   |.||||.
plant   247 VLGLPYLQGQDKRQFSMYFYLPDANNGLSDLLDKIVSTPGFLD--NHIPRRQVKVREFKIPKFKF 309

  Fly   275 DYSLELAEKLKQLGITKMFTDQAEFSNLLESPE---GVFVSKVLHKATIEVNEEGTEAAAATGMI 336
            .:..:.:..||.||:|..|:.:...:.::||||   .:.||.:.|||.|||||||||||||:..:
plant   310 SFGFDASNVLKGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGV 374

  Fly   337 MMTR---MMTFPLQFQADRPFLYVIWNKKNI----LFAGAFV 371
            :..|   |....:.|.||.|||.|:  .:||    ||.|..|
plant   375 IKLRGLLMEEDEIDFVADHPFLLVV--TENITGVVLFIGQVV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	120/364 (33%)
SERPIN1	NP_001320925.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970