DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and Serpina7

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_112390.1	Gene:	Serpina7 / 81806	RGDID:	619833	Length:	426	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	116/375 - (30%)
Similarity:	191/375 - (50%)	Gaps:	27/375 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPP--EVAQT 75
            |.|...|::.||......|:.|||.||...:|:...||...|..:|.:.|.|.....|  |:.|.
  Rat    58 ADFAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTDTPVKELQQG 122

  Fly    76 FQFVL--EKYRNSNL-LRVANKLYVQEGKQLKP--AYQSAIKEQYHSEAESINFALNDAAAQAIN 135
            ||.::  ..:.|:.| |::.|.:::  |:||||  .:...:|..|.:|..|.:|:...||...||
  Rat   123 FQHLICSLNFPNNELELQMGNAVFI--GQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEIN 185

  Fly   136 AWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDI-FWVGEEEQVKINY 199
            ::|..:|:|||..|:  .....|..::|:|.:|||..||:.|...:|||.. |.|.:...|::..
  Rat   186 SYVEKQTKGKIVGLI--QDLKLNIIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPM 248

  Fly   200 MNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIY---ALAEK-LKTVNLVDLADKL 260
            |:|..::.:....:|.||.|:|.|..:.|::|| ||:|....:   |::.| ||..|  .|..|.
  Rat   249 MHQLEQYYHYVDVELNCTVLQMDYSANALALFV-LPKEGHMEWVEAAMSSKTLKKWN--HLLQKG 310

  Fly   261 TVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEE 325
            .||   :..|||.:..:.:|...|:::|:...|.:.|:|..:.:. .|:.:|...|||.:.:.||
  Rat   311 WVE---LFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITKD-NGLKLSYAFHKAVLHIGEE 371

  Fly   326 GTEAAAATGMIMMTRMMTFPLQ--FQADRPFLYVIWNK--KNILFAGAFV 371
            ||:..|:.....:.:....||.  .:.||.||.:|..|  :::||.|..|
  Rat   372 GTKEGASPEAGSLDQPEVAPLHAVIRLDRTFLLMILEKRTRSVLFLGKVV 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	115/372 (31%)
Serpina7	NP_112390.1	serpinA7_TBG	48..425	CDD:381023	116/375 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010