Protein Alignment Spn55B and Serpinb12

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_082247.1
• Gene: Serpinb12 / 71869
• MGIID: 1919119
• Length: 423
• Species: Mus musculus
• Alignment Length: 410
• Identity: 117/410 - (28%)
• Similarity: 210/410 - (51%)
• Gaps: 56/410 - (13%)

  Fly    14 RFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF---------VSNFP 69
            :|..:.|:.:|.....:|:...|.|:.....:...|::|::|.:|.:||||         ..|.|
Mouse    10 KFCFDFFREISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAHQIDEALHFNELSKDEHKEPNDP 74

  Fly    70 P--------------------------EVAQTFQFV----------LEKYRNSNLLRVANKLYVQ 98
            .                          |.....|.:          :::.::...|.:||:||.:
Mouse    75 SPQSESKASDSSLEGQKQTSASQDQQGESTNDHQLLGCHFGKLLSRIDRDKSYYTLSMANRLYGE 139

  Fly    99 EGKQLKPAYQSAIKEQYHSEAESINFAL-NDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLV 162
            :...:...|...:.|.:|:..||::|.. ::.:.|.||.||.:::||||.||...::..::|.||
Mouse   140 QEFPICSEYSDDVTEFFHTTVESVDFQKDSEKSRQEINFWVESQSQGKIKELFGKEAIDNSTVLV 204

  Fly   163 LLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSD 227
            |:||::||..|..:|:.|.|.:..|.:.|.|:..:..||||.||..||.::|....|||.|....
Mouse   205 LVNAVYFKAKWEREFNSENTVDASFCLNENEKKTVKMMNQKGKFRIGFIDELQAQILEMKYAMGK 269

  Fly   228 LSMFVLLPQ-ERTGIYALAEKLKTVNLVDL-----ADKLTVEEVHVKFPKFKVDYSLELAEKLKQ 286
            |||.||||. ....:.:|.|..|.:|...|     ::.|:.:.|.:.||:|.::.|.:|...|:.
Mouse   270 LSMLVLLPSCSEDNVNSLQELEKKINHEKLLAWSSSENLSEKPVAISFPQFNLEDSYDLKSILQD 334

  Fly   287 LGITKMFTD-QAEFSNLLESPEGVFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQA 350
            :||..:|.: :|:.:.:.:|| .:::||::||..:||:|.||:||||:|::...:.:...::|.|
Mouse   335 MGIKDVFDETKADLTGISKSP-NLYLSKIVHKTFVEVDEMGTQAAAASGVVAAEKALPSWVEFNA 398

  Fly   351 DRPFLYVIWNK--KNILFAG 368
            :.|||:.|.:.  :::||.|
Mouse   399 NHPFLFFIRHNPTQSLLFCG 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	116/407 (29%)
Serpinb12	NP_082247.1	serpinB12_yukopin	1..423	CDD:381037	117/410 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..106		3/42 (7%)