DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and Serpine3

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	100/375 - (26%)
Similarity:	178/375 - (47%)	Gaps:	31/375 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FARGG------------ARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAK 60
            |:.||            ..|...|:|..:|.....|.|.||.|:...:.:....::|.|..::|:
  Rat    16 FSAGGGSPLSEGLWLLKTEFALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAE 80

  Fly    61 ALHFVSNFPPEVAQTFQFVLEKYRNSNL---LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESI 122
            ||.:... .|.|.:....|.....||:.   :.:|..|::|.|..|.|.:...:....:|..|..
  Rat    81 ALGYTVQ-DPRVREFLHTVYITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVSRWANSSLELA 144

  Fly   123 NFA-LNDAAAQAINAWVNAKT-QGKITELVS-ADSFSDNTRLVLLNALHFKGSWAHKFSEERTEE 184
            :|: .|....:|........| :|..:.|.. |.:.|  |:|.:::.:.|:.||..:||....:.
  Rat   145 DFSEPNTTTMEASKGTTRPSTGEGPGSPLWGRAGALS--TQLSIVSTMTFQSSWQQRFSSVALQP 207

  Fly   185 DIFWVGEEEQVKINYMNQKAKFNYGFFEDLG---CTALEMPYQDSDLSMFVLLPQERTGIYALAE 246
            ..|.......:::..|:|.|:.:||.|:|..   ...||:.|.....|:.::|||::.......|
  Rat   208 LPFTCAHGLVLQVPAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQDKGTPLDHIE 272

  Fly   247 KLKTVNLVDL-ADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNL--LESPEG 308
            ...|..::.| ..:|....:.|..|:|::....:|...|:..|||.:| |..: :||  :...:|
  Rat   273 PHLTARVIHLWTTRLKRARMDVFLPRFRIQNQFDLKSILRSWGITDLF-DPLK-ANLKGISGRDG 335

  Fly   309 VFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVI 358
            .:||:|.|||.:|::||||::.|||.::::.|..| | .|:|||||::::
  Rat   336 FYVSEVTHKAKMELSEEGTKSCAATAVLLLRRSRT-P-AFKADRPFIFLL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	97/358 (27%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	98/371 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020