Protein Alignment Spn55B and Serpina12

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 367
• Identity: 97/367 - (26%)
• Similarity: 185/367 - (50%)
• Gaps: 32/367 - (8%)

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFP 69
            :.||....|..:|.|.|::...:.|:..||.||.|..::...|:|..|.:||.:..:|  :||:
Mouse    47 QLARHNMEFGFKLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNW- 110

  Fly    70 PEVAQTFQFVLEKYR---NSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAA 131
             :|...|.::|.|..   ....:.:.|.|::.:..:.:..:.:..|..|.::....||...:...
Mouse   111 -DVHAAFHYLLHKLNQETEDTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQ 174

  Fly   132 QAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVK 196
            :.||.:::.||..:|..:|.  |....|.::|.|.::|:|.|.::|..::|:|:.|::.:.:.||
Mouse   175 KDINRYISQKTHSRIKNMVK--SIDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVK 237

  Fly   197 INYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFV--------LLPQE-RTGIYALAEKLKTVN 252
            :..|.|:..::..:...|.||.||:||:.:..:.||        ||.|. :..|:|..:.|.:..
Mouse   238 VPMMFQRGLYDMAYDSQLSCTILEIPYRGNITATFVLPDNGKLKLLEQGLQADIFAKWKSLLSKR 302

  Fly   253 LVDLADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHK 317
            :||           |..||.::..:..:.:.|.:|||:|:|.:..:.:. :.|...:.|.:.:||
Mouse   303 VVD-----------VWVPKLRISSTYNMKKVLSRLGISKIFEENGDLTR-ISSHRSLKVGEAVHK 355

  Fly   318 ATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIW 359
            |.::::|:|.|.||.:|  ..|..|..|...:.|||||.:|:
Mouse   356 AELKMDEKGMEGAAGSG--AQTLPMETPRHMKLDRPFLMMIY 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	95/361 (26%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	95/363 (26%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		7/19 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010