Protein Alignment Spn55B and SERPINB4

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 140/388 - (36%)
• Similarity: 212/388 - (54%)
• Gaps: 31/388 - (7%)

  Fly     9 ARGGARFTSELFQLLSAGGLKENVVF-SPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFPP 70
            :....:|..:|||.....  |||.:| ||.||.:.:.:...|::..||.:|:|.|||  |:....
Human     5 SEANTKFMFDLFQQFRKS--KENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTT 67

  Fly    71 EVAQT------------FQFVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAE 120
            |.|.|            ||.:|.::..|.   .|::||||:.::..|....|..|||:.|.:..|
Human    68 EKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVE 132

  Fly   121 SINFA-LNDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEE 184
            |.:|| ..:.:.:.||:||.::|..||..|....:..::|.|||:||::|||.|.:||.:|.|:|
Human   133 STDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKE 197

  Fly   185 DIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLK 249
            :.||..:.....:..|.|...||:...||:....||:||:..||||.||||.|..|:..|.|||.
Human   198 EKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLT 262

  Fly   250 TVNLVDLADKLTVEE--VHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVS 312
            ...|::......:.|  |.:..|:||::.|.:|.:.|:.:|:..:|...|:.|.:..| .|:.||
Human   263 AEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWS-HGLSVS 326

  Fly   313 KVLHKATIEVNEEGTEAAAATGMIMMTRMMTFPL---QFQADRPFLYVI-WNKKN-ILFAGAF 370
            ||||||.:||.|||.||||||.::::.  ::.|.   :|..:.|||:.| .||.| |||.|.|
Human   327 KVLHKAFVEVTEEGVEAAAATAVVVVE--LSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRF 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	138/378 (37%)
SERPINB4	NP_002965.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	140/388 (36%)