Protein Alignment Spn55B and SERPINI2

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_006208.1
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 115/367 - (31%)
• Similarity: 194/367 - (52%)
• Gaps: 9/367 - (2%)

  Fly     9 ARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE-- 71
            |:....|..:|:|.:|... |:|::|||..|...:.:...|::|:...:|.:.|........|
Human    23 AQKNTEFAVDLYQEVSLSH-KDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86

  Fly    72 -VAQTFQFVLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAIN 135
             |.::|...:.:.:......:||.||:|||..:|..|....||.:.|..:.::|....|.|:.|:
Human    87 FVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMIS 151

  Fly   136 AWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYM 200
            .||..||.|||.::.|.:.|...|||||:||::|||.|..||.:|.|:...|.......|||..|
Human   152 TWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMM 216

  Fly   201 NQKAKFNYGFFED--LGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLTVE 263
            ....:..||:|.:  |....||:.|:..:.|:.::||.|...|..:.:.:....::....::..|
Human   217 KALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEE 281

  Fly   264 EVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTE 328
            ||.:..|:|||:..::..:.|..|.||::|:...:.|.:.:|.| |:||:|..|...|:||:|:|
Human   282 EVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSE-VYVSQVTQKVFFEINEDGSE 345

  Fly   329 AAAATGMIMMTRMMTFPLQFQADRPFLYVIWNK--KNILFAG 368
            ||.:||:.:...|.....||.|:.|||:::.:.  ::|||.|
Human   346 AATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMG 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	113/359 (31%)
SERPINI2	NP_006208.1	serpinI2_pancpin	23..392	CDD:381042	115/367 (31%)