Protein Alignment Spn55B and SERPINB13

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 119/374 - (31%)
• Similarity: 191/374 - (51%)
• Gaps: 36/374 - (9%)

  Fly    31 NVVFSPFSIQTCIALAFAGSQGETADEIAKALHF-------------------------VSNFPP 70
            |:.|||..|.|.|.:...|::|.||.::.:..|.                         :.| ..
Human    26 NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRIKAEGKEIEN-TE 89

  Fly    71 EVAQTFQ-FVLE--KYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFA-LNDAAA 131
            .|.|.|| |:.|  |..|...|.:.|:|:.::.......|...:::.||:..|.::|. ..|.:.
Human    90 AVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESR 154

  Fly   132 QAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVK 196
            :.||:||.:||..||.:|....|.|.:|:|||:|.::|||.|..:|.:|.|:|:.||:.:.....
Human   155 KKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKS 219

  Fly   197 INYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLT 261
            :..|.|...|::.|.|||....|.:||:::|||||||||.:..|:..:.:|:....||:......
Human   220 VQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGH 284

  Fly   262 VEE--VHVKFPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPEGVFVSKVLHKATIEVN 323
            :||  |::..|:|:|:...:|...|..:|:...|:: :|::|. :.|..|::..|.||.:.:.|.
Human   285 MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSG-MSSGSGLYAQKFLHSSFVAVT 348

  Fly   324 EEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVI-WNKKN-ILFAGAF 370
            |||||||||||:...............:.|||:.| .|:.| |||.|.|
Human   349 EEGTEAAAATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRF 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	118/372 (32%)
SERPINB13	NP_001294852.1	SERPIN	4..400	CDD:294093	119/374 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830