Protein Alignment Spn55B and SERPINI1

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 125/380 - (32%)
• Similarity: 206/380 - (54%)
• Gaps: 28/380 - (7%)

  Fly    12 GARFTSE--------LFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNF 68
            ||.|..|        ::..|.|.|..||::|||.||...:.:...|:||.|..||..::.:.|
Human    18 GATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDS-- 80

  Fly    69 PPEVAQTFQFVLEKYRN-------SNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFAL 126
             .:..:.|.| |:::.|       ..::::||.|:||.|..:...:...:|:.:::....::|:.
Human    81 -LKNGEEFSF-LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143

  Fly   127 NDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGE 191
            |.|.|..||.||...|...:.:|||...|...|.|.|:||::|||:|..:|..|.|....|...:
Human   144 NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208

  Fly   192 EEQVKINYMNQKAKFNYGFFEDLGCTA------LEMPYQDSDLSMFVLLPQERTGIYALAEKLKT 250
            |.:|:|..|.|:.:|.||.|.|....|      ||:||:..::||.::|.::...:..|...:|.
Human   209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKA 273

  Fly   251 VNLVDLADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVL 315
            ..:.:.|:.:..::|.|..|:|.|:..::|.:.||.||||::|...|..:.|.::.| :|:||.:
Human   274 QLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKE-IFLSKAI 337

  Fly   316 HKATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKK--NILFAG 368
            ||:.:||||||:||||.:|||.::||.....|...|.||.::|.|::  .|||.|
Human   338 HKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMG 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	124/379 (33%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	122/375 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21045
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm9820
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.830