Protein Alignment Spn55B and SERPINB8

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 129/374 - (34%)
• Similarity: 214/374 - (57%)
• Gaps: 15/374 - (4%)

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE 71
            :.......|...||::|.......||.|||.||.:.:|:.|.|::|.||.::::||....:  .:
Human     3 DLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD--GD 65

  Fly    72 VAQTFQFVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALN-DAAAQ 132
            :.:.||.:|.:...:.   |||.||:|:.::.....|.::...::.|.:|.|.::||.: :...:
Human    66 IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRK 130

  Fly   133 AINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKI 197
            .||.||..||:|||:|::.|.:....|:|||:||::|||.|..:|..:.|...:|...||::. :
Human   131 HINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-V 194

  Fly   198 NYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDL---ADK 259
            ..|.::|||..|:.:::....||:||.:.:|||.:|||.:.|.: |:.||..|......   ::|
Human   195 QMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDL-AVVEKALTYEKFKAWTNSEK 258

  Fly   260 LTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPEGVFVSKVLHKATIEVN 323
            ||..:|.|..|:.|::.|.:|...|::||:...|.: :|:||. :.:.:.|.:|||.||..:|||
Human   259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSG-MSTEKNVPLSKVAHKCFVEVN 322

  Fly   324 EEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN--ILFAGAF 370
            ||||||||||.::..:|......:|.||.|||:.|.:.|.  |||.|.|
Human   323 EEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRF 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	127/362 (35%)
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	129/374 (34%)